Results 181 to 190 of about 22,086 (209)
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Canadian Journal of Biochemistry, 1965
Several aspects of the metabolism of inosine and uridine by Ehrlich ascites carcinoma cells in vitro have been found to be inhibited by ribonucleoside derivatives of four purine analogues. The synthesis of both inosine and uridine by intact tumor cells was profoundly inhibited in the presence of 6-methylmercaptopurine ribonucleoside.
A R, Paterson, A I, Simpson
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Several aspects of the metabolism of inosine and uridine by Ehrlich ascites carcinoma cells in vitro have been found to be inhibited by ribonucleoside derivatives of four purine analogues. The synthesis of both inosine and uridine by intact tumor cells was profoundly inhibited in the presence of 6-methylmercaptopurine ribonucleoside.
A R, Paterson, A I, Simpson
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Didesoxy-Ribonucleoside durch Schmelzkondensation
Journal f�r Praktische Chemie/Chemiker-Zeitung, 1993Dideoxy Ribonucleosides by Fusion Method The dideoxy nucleosides 2, 4 and 6 are synthesized from the 1-O-acetyl-2,3-dideoxyribose derivatives 1, 3 and 5 by fusion with chlorinated purines and other nitrogen heterocycles at 110–120°C without added catalyst. The 1H-NMR and 13C-NMR spectra of the compounds are given.
Elke Diekmann +2 more
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Ribonucleoside 2′,3′-orthocarbonates
J. Chem. Soc. D, 1969Ribonucleosides undergo acid-catalysed exchange with tetramethyl orthocarbonate to give 2′,3′-O-dimethoxymethylidene derivatives.
G. R. Niaz, C. B. Reese
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Reduction of Ribonucleosides to 2′‐Deoxyribonucleosides
Current Protocols in Nucleic Acid Chemistry, 2005AbstractRibonucleosides are converted into 2′‐deoxyribonucleosides in good yields by a four‐step procedure. Selective protection of the 3′‐ and 5′‐hydroxyl groups with 1,3‐dichloro‐1,1,3,3‐tetraisopropyl‐1,3‐disiloxane is followed by functionalization of the 2′‐hydroxyl group with phenoxythiocarbonyl chloride.
Morris J, Robins, Stanislaw F, Wnuk
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Synthesis of 2′-O-Substituted Ribonucleosides
Nucleosides, Nucleotides and Nucleic Acids, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
V, Serebryany, L, Beigelman
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Über substituierte 2.3‐Benzyliden‐ribonucleoside
Justus Liebigs Annalen der Chemie, 1964AbstractDie Darstellung von [4‐Dimethylamino‐benzyliden]‐ und [2.4‐Dimethoxy‐benzyliden]‐ribonucleosiden wird beschrieben. Diese Verbindungen werden rasch unter milden sauren Bedingungen hydrolysiert und lassen sich mit 2‐Cyanäthylphosphat/Dicyclohexylcarbodiimid phosphorylieren.
Friedrich Cramer +3 more
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Selective deacylation of peracylated ribonucleosides
Tetrahedron Letters, 2009Abstract A protocol for chemoselective deprotection of N,O-acylated ribonucleosides has been developed. Peracylated pyrimidine ribonucleosides subjected to guanidinium nitrate and NaOMe in MeOH/CH 2 Cl 2 at 0 °C undergo high yielding O-deacylation, while even more pronounced chemoselectivity is observed with peracylated purine ribonucleosides as O5′-
Jared W. Rigoli +4 more
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[18] Ribonucleoside cyclic phosphates
1967Publisher Summary This chapter discusses ribonucleoside cyclic phosphates and their methods of preparation. Ribonucleoside cyclic phosphates refer to the 2', 3'-monophosphate esters of nucleosides. They are originally isolated as intermediates during the enzymatic or mild alkaline degradations of ribonucleic acids, and independently and ...
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2-Fluoropurine ribonucleosides
Journal of Medicinal Chemistry, 1970J A, Montgomery, K, Hewson
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2′--acyl ribonucleoside derivatives
Tetrahedron Letters, 1965C B, Reese, D R, Trentham
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