Results 21 to 30 of about 181,495 (258)

Characterization of a second class Ie ribonucleotide reductase [PDF]

Communications Biology
Class I ribonucleotide reductases (RNRs) convert ribonucleotides into deoxyribonucleotides under oxic conditions. The R2 subunit provides a radical required for catalysis conducted by the R1 subunit. In most R2s the radical is generated on a tyrosine via
Juliane John, Daniel Lundin, Rui M. Branca, Rohit Kumar, Vivek Srinivas, Hugo Lebrette, Martin Högbom   +6 more
doaj   +2 more sources

Choosing the right metal: case studies of class I ribonucleotide reductases. [PDF]

J Biol Chem, 2014
Over one-third of all proteins require metallation for function (Waldron, K. J., Rutherford, J. C., Ford, D., and Robinson, N.J. (2009) Nature 460, 823–830).
Huang M, Parker MJ, Stubbe J.
europepmc   +2 more sources

Ribonucleotide reductases reveal novel viral diversity and predict biological and ecological features of unknown marine viruses. [PDF]

Proc Natl Acad Sci U S A, 2014
Sakowski EG, Munsell EV, Hyatt M, Kress W, Williamson SJ, Nasko DJ, Polson SW, Wommack KE.   +7 more
europepmc   +2 more sources

Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo. [PDF]

Annu Rev Biochem, 2011
Cotruvo JA, Stubbe J.
europepmc   +2 more sources

Methodology to probe subunit interactions in ribonucleotide reductases. [PDF]

Biochemistry, 2008
Hassan AQ, Wang Y, Plate L, Stubbe J.
europepmc   +2 more sources

Narrow and Stripe Leaf 2 Regulates Leaf Width by Modulating Cell Cycle Progression in Rice

Rice, 2023
Background Leaf morphology is an important component of the idea plant architecture that extensively influences photosynthesis, transpiration, and ultimately grain yield in crops.
Wenqiang Shen, Jiajie Sun, Zan Xiao, Ping Feng, Ting Zhang, Guanghua He, Xianchun Sang   +6 more
doaj   +1 more source

Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer [PDF]

, 2015
Ribonucleotide reductases (RNRs) are responsible for all de novo biosynthesis of DNA precursors in nature by catalyzing the conversion of ribonucleotides to deoxyribonucleotides. Because of its essential role in cell division, human RNR is a target for a
Ando, Nozomi, Asturias, Francisco J., Brignole, Edward J, Drennan, Catherine L., Li, Haoran, McLaughlin, Martin I., Page, Julia E., Stubbe, JoAnne, Thompson, Samuel M.   +8 more
core   +5 more sources

Non-host class II ribonucleotide reductase in Thermus viruses: sequence adaptation and host interaction [PDF]

PeerJ, 2019
Ribonucleotide reductases (RNR) are essential enzymes for all known life forms. Their current taxonomic distribution suggests extensive horizontal gene transfer e.g., by processes involving viruses.
Christoph Loderer, Karin Holmfeldt, Daniel Lundin   +2 more
doaj   +2 more sources

Pseudomonas aeruginosa Nonphosphorylated AlgR Induces Ribonucleotide Reductase Expression under Oxidative Stress Infectious Conditions

mSystems, 2023
Ribonucleotide reductases (RNRs) are key enzymes which catalyze the synthesis of deoxyribonucleotides, the monomers needed for DNA replication and repair.
Alba Rubio-Canalejas, Joana Admella, Lucas Pedraz, Eduard Torrents   +3 more
doaj   +1 more source

Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase [PDF]

, 2005
Ribonucleotide reductases (RNRs) catalyze the production of deoxyribonucleotides, which are essential for DNA synthesis and repair in all organisms.
Atkin, Bennati, Bennati, Denysenkov, Ehrenberg, Kolberg, Ling, Mezyk, Milov, Oelgemöller, Schmittel, Sjöberg, Sjöberg, Steenken, Stubbe, Stubbe, Thelander, Thelander   +17 more
core   +2 more sources