Results 61 to 70 of about 181,495 (258)

Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family

Human Genomics, 2006
The NAD(P)H:quinone acceptor oxidoreductase (NQO) gene family belongs to the flavoprotein clan and, in the human genome, consists of two genes (NQO1 and NQO2).
Vasiliou Vasilis, Ross David, Nebert Daniel W   +2 more
doaj   +1 more source

Bacteriophage‐Induced Ribonucleotide Reductase Systems [PDF]

European Journal of Biochemistry, 1974
Infection of Escherichia coli with bacteriophage T5 caused a more than 20‐fold increase in ribonucleotide reductase activity in crude cell extracts. The phage induced the formation of a new ribonucleotide reductase and a new thioredoxin.The T5‐specific ribonucleotide reductase was defined by its ability to accept the T5‐induced thioredoxin as hydrogen ...
S, Eriksson, O, Berglund
openaire   +2 more sources

Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes [PDF]

, 2013
Biochemical reactions, even those as complex as replicating the DNA genome of cells, follow the principle that the process is regulated by both the substrate concentration and by the enzymes that mediate the process. Deoxynucleoside triphosphates (dNTPs),
Stillman, B.
core   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage [PDF]

, 2017
The NADPH-dependent homodimeric flavoenzyme thioredoxin reductase (TrxR) provides reducing equivalents to thioredoxin, a key regulator of various cellular redox processes. Crystal structures of photo-inactivated thioredoxin reductase (TrxR) from the Gram-
Bang, Maria Blanner, Björnberg, Olof, Davies, Michael J., Harris, Pernille, Hägglund, Per, Rykær, Martin, Skjoldager, Nicklas, Svensson, Birte   +7 more
core   +2 more sources

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues [PDF]

, 2008
RNA viruses exhibit extraordinarily high mutation rates during genome replication. Nonnatural ribonucleosides that can increase the mutation rate of RNA viruses by acting as ambiguous substrates during replication have been explored as antiviral agents ...
Barr, Eric W., Bollinger, J. Martin, Jr., Brown, Daniel M., Cameron, Craig E., Edathil, Jocelyn P., Galarraga, Jessica E., Graci, Jason D., Harki, Daniel A., Loakes, David, Peterson, Blake R., Smidansky, Eric D., Too, Kathleen   +11 more
core   +4 more sources

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Family A DNA Polymerase Phylogeny Uncovers Diversity and Replication Gene Organization in the Virioplankton

Frontiers in Microbiology, 2018
Shotgun metagenomics, which allows for broad sampling of viral diversity, has uncovered genes that are widely distributed among virioplankton populations and show linkages to important biological features of unknown viruses. Over 25% of known dsDNA phage
Daniel J. Nasko, Jessica Chopyk, Eric G. Sakowski, Barbra D. Ferrell, Shawn W. Polson, K. Eric Wommack   +5 more
doaj   +1 more source

Photochemical Generation of a Tryptophan Radical within the Subunit Interface of Ribonucleotide Reductase [PDF]

, 2016
United States.
Brandon L. Greene, Chelsea Finkbeiner, Daniel G. Nocera, JoAnne Stubbe, Lisa Olshansky, Lunn C. A.   +5 more
core   +3 more sources