Results 141 to 150 of about 246,720 (281)

Expression of cyclic ADP-ribose-synthetizing CD38 molecule on human platelet membrane [PDF]

open access: bronze, 1996
Giuseppe Ramaschi   +5 more
openalex   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal   +14 more
wiley   +1 more source

Figure S1 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer

open access: gold, 2023
Aditi Jain   +23 more
openalex   +2 more sources

Overexpression of an ADP‐ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants [PDF]

open access: bronze, 2008
Takahisa Ogawa   +5 more
openalex   +1 more source

D‑ribose: Potential clinical applications in congestive heart failure and diabetes, and its complications (Review)

open access: diamond, 2021
Shuai Li   +8 more
openalex   +2 more sources

One‐Stone‐Three‐Birds Biomimetic Oral Targeting Delivery Strategy for On‐Demand Controlled Drug Release and Intervertebral Disc Degeneration Therapy

open access: yesExploration, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a multifactorial condition characterized by excessive inflammation, immune dysfunction, and metabolic disorders. Current therapeutic strategies primarily rely on local injection, a traumatic approach associated with risks of tissue damage and infection.
Yifan Ding   +8 more
wiley   +1 more source

Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage

open access: diamond, 2018
Lisa Beatrice Caruso   +8 more
openalex   +2 more sources

Advances in Double‐Stranded DNA Targeting Technologies

open access: yesExploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen   +8 more
wiley   +1 more source

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes [PDF]

open access: gold, 2008
Jean-Philippe Gagné   +7 more
openalex   +1 more source

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