Results 11 to 20 of about 246,720 (281)
Effect of Aliphatic Aldehydes on Flavor Formation in Glutathione–Ribose Maillard Reactions
The Maillard reaction (MR) is affected by lipid oxidation, the intermediate products of which are key to understanding this process. Herein, nine aliphatic aldehyde–glutathione–ribose models were designed to explore the influence of lipid oxidation ...
Hao Liu +7 more
doaj +1 more source
Effect of ribose-glycated BSA on histone demethylation
A reducing sugar reacts with the protein, resulting in advanced glycation end-products (AGEs), which have been implicated in diabetes-related complications.
Mengqi Xi +7 more
doaj +1 more source
Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription [PDF]
TET enzymes are the epigenetic factors involved in the formation of the Sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis.
Bacalini, MARIA GIULIA +9 more
core +12 more sources
The aim of this study was to compare the kinetics of the glycoxidation of bovine serum albumin (BSA) as a model protein by three sugars: glucose, fructose and ribose, using fluorometric measurements of the content of advanced glycation end products (AGEs)
Izabela Sadowska-Bartosz +2 more
doaj +1 more source
Previous studies have shown that the association of the drug meglumine antimoniate (MA) with β-cyclodextrin can improve its bioavailability by the oral route.
Weverson A. Ferreira +5 more
doaj +1 more source
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage [PDF]
The molecular role of poly (ADP-ribose) polymerase-1 in DNA repair is unclear. Here, we show that the single-strand break repair protein XRCC1 is rapidly assembled into discrete nuclear foci after oxidative DNA damage at sites of poly (ADP-ribose ...
Caldecott, Keith W. +3 more
core +2 more sources
Possible Ribose Synthesis in Carbonaceous Planetesimals
The origin of life might be sparked by the polymerization of the first RNA molecules in Darwinian ponds during wet-dry cycles. The key life-building block ribose was found in carbonaceous chondrites.
Klaus Paschek +7 more
doaj +1 more source
APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells [PDF]
APLF is a novel protein of unknown function that accumulates at sites of chromosomal DNA strand breakage via forkhead-associated (FHA) domain-mediated interactions with XRCC1 and XRCC4.
Caldecott, Keith W +4 more
core +3 more sources
Spatial and temporal cellular responses to single-strand breaks in human cells [PDF]
DNA single-strand breaks (SSB) are one of the most frequent DNA lesions produced by reactive oxygen species and during DNA metabolism, but the analysis of cellular responses to SSB remains difficult due to the lack of an experimental method to produce ...
Caldecott, Keith W +4 more
core +4 more sources
Safety of d‐ribose as a novel food pursuant to Regulation (EU) 2015/2283
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on D‐ribose as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) +27 more
doaj +1 more source

