Results 11 to 20 of about 246,720 (281)

Effect of Aliphatic Aldehydes on Flavor Formation in Glutathione–Ribose Maillard Reactions

open access: yesFoods, 2023
The Maillard reaction (MR) is affected by lipid oxidation, the intermediate products of which are key to understanding this process. Herein, nine aliphatic aldehyde–glutathione–ribose models were designed to explore the influence of lipid oxidation ...
Hao Liu   +7 more
doaj   +1 more source

Effect of ribose-glycated BSA on histone demethylation

open access: yesFrontiers in Genetics, 2022
A reducing sugar reacts with the protein, resulting in advanced glycation end-products (AGEs), which have been implicated in diabetes-related complications.
Mengqi Xi   +7 more
doaj   +1 more source

Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription [PDF]

open access: yes, 2014
TET enzymes are the epigenetic factors involved in the formation of the Sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis.
Bacalini, MARIA GIULIA   +9 more
core   +12 more sources

Kinetics of Glycoxidation of Bovine Serum Albumin by Glucose, Fructose and Ribose and Its Prevention by Food Components

open access: yesMolecules, 2014
The aim of this study was to compare the kinetics of the glycoxidation of bovine serum albumin (BSA) as a model protein by three sugars: glucose, fructose and ribose, using fluorometric measurements of the content of advanced glycation end products (AGEs)
Izabela Sadowska-Bartosz   +2 more
doaj   +1 more source

Mixed Antimony(V) Complexes with Different Sugars to Modulate the Oral Bioavailability of Pentavalent Antimonial Drugs

open access: yesMolecules, 2014
Previous studies have shown that the association of the drug meglumine antimoniate (MA) with β-cyclodextrin can improve its bioavailability by the oral route.
Weverson A. Ferreira   +5 more
doaj   +1 more source

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage [PDF]

open access: yes, 2003
The molecular role of poly (ADP-ribose) polymerase-1 in DNA repair is unclear. Here, we show that the single-strand break repair protein XRCC1 is rapidly assembled into discrete nuclear foci after oxidative DNA damage at sites of poly (ADP-ribose ...
Caldecott, Keith W.   +3 more
core   +2 more sources

Possible Ribose Synthesis in Carbonaceous Planetesimals

open access: yesLife, 2022
The origin of life might be sparked by the polymerization of the first RNA molecules in Darwinian ponds during wet-dry cycles. The key life-building block ribose was found in carbonaceous chondrites.
Klaus Paschek   +7 more
doaj   +1 more source

APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells [PDF]

open access: yes, 2008
APLF is a novel protein of unknown function that accumulates at sites of chromosomal DNA strand breakage via forkhead-associated (FHA) domain-mediated interactions with XRCC1 and XRCC4.
Caldecott, Keith W   +4 more
core   +3 more sources

Spatial and temporal cellular responses to single-strand breaks in human cells [PDF]

open access: yes, 2003
DNA single-strand breaks (SSB) are one of the most frequent DNA lesions produced by reactive oxygen species and during DNA metabolism, but the analysis of cellular responses to SSB remains difficult due to the lack of an experimental method to produce ...
Caldecott, Keith W   +4 more
core   +4 more sources

Safety of d‐ribose as a novel food pursuant to Regulation (EU) 2015/2283

open access: yesEFSA Journal, 2018
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on D‐ribose as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)   +27 more
doaj   +1 more source

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