Results 271 to 280 of about 246,720 (281)

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2. [PDF]

Elife
Suryawanshi RK, Jaishankar P, Correy GJ, Rachman MM, O'Leary PC, Taha TY, Matsui Y, Zapatero-Belinchón FJ, McCavitt-Malvido M, Doruk YU, Stevens MGV, Diolaiti ME, Jogalekar MP, Chen H, Richards AL, Kongpracha P, Bali S, Montano M, Rosecrans J, Matthay M, Togo T, Gonciarz RL, Gopalkrishnan S, Neitz RJ, Krogan NJ, Swaney DL, Shoichet BK, Ott M, Renslo AR, Ashworth A, Fraser JS.   +30 more
europepmc   +1 more source

Poly(ADP-ribose) polymerase (PARP) inhibitors for BRCA-associated early triple-negative breast cancer: progress and future hopes

Sh. R. Abdullaeva, Т. Yu. Semiglazova, A. S. Artemyeva, Татьяна Ивановна Севостьянова, Л. В. Филатова, В. В. Семиглазов, Petr Krivorotko, Semiglazov Vf   +7 more
openalex   +1 more source

Determination of nucleotide-nucleotide and nucleotide-amino acid binding interactions from all-atom potential-of-mean-force calculations

Feito A, Pedraza E, Cuesta E, Castro A, Sanchez-Burgos I, Rey A, Collepardo-Guevara R, Tejedor AR, Espinosa JR.   +8 more
europepmc   +1 more source

Correction to "OTUB1 Modulates Ferroptosis by Regulating SLC7A11 Ubiquitination in Pancreatic β-Cells". [PDF]

FASEB J
europepmc   +1 more source

Genome-wide ribonucleotide detection in Archaea. [PDF]

Nucleic Acids Res
Moalic Y, Reveil M, Kundnani DL, Balachander S, Yang T, Gombolay A, Ranjbarian F, Brizard R, Durand P, Myllykallio H, Jebbar M, Hofer A, Storici F, Henneke G.   +13 more
europepmc   +1 more source

Gold Mono- and Bis-N-heterocyclic Carbenes Based on mRNA cap0. [PDF]

ACS Omega
Francescato G, Orsini G, Petronilho A.
europepmc   +1 more source

Ten novel psychrophilic <i>Flavobacterium</i> species from Tibetan Plateau glaciers define a cryospheric lineage with global cold-origin relatives. [PDF]

Int J Syst Evol Microbiol
Liu Q, Yang LL, Xin YH.
europepmc   +1 more source

Catabolic rewiring in cancer impacts dietary interventions. [PDF]

Commun Biol
Chinopoulos C.
europepmc   +1 more source