Results 41 to 50 of about 246,720 (281)
d-Ribose as a Contributor to Glycated Haemoglobin
EBioMedicine, 2017 Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c.
Xixi Chen +8 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Biota. Human. TechnologyThe interplay between diabetes mellitus and the structural integrity of collagen has significant implications for tissue functionality and disease progression.
Kateryna Topchylo, Halina Tkaczenko
doaj +1 more source
D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway
Frontiers in Cell and Developmental Biology, 2019 D-ribose levels are demonstrated to be increased in type II diabetes mellitus and increased blood D-ribose is involved in the development of diabetic complications such as diabetic encephalopathy and nephropathy.
Jinni Hong +7 more
doaj +1 more source
Borate-guided ribose phosphorylation for prebiotic nucleotide synthesis
Scientific Reports, 2022 Polymers of ribonucleotides (RNAs) are considered to store genetic information and promote biocatalytic reactions for the proto life on chemical evolution.
Yuta Hirakawa +2 more
doaj +1 more source
Shipin gongye ke-ji, 2022 Study the effects of aerobic exercise combined with D-ribose supplementation on the anti-fatigue and antioxidant enzyme activities of mice, the mice were divided into quiet control group, aerobic exercise control group, D-ribose control group, D-ribose ...
Zhengang ZHANG, Feng WANG
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors
Haematologica, 2008 Poly ADP-ribose polymerase inhibitors have been shown to target cells with homologous recombination DNA repair defects. We report that poly ADP-ribose polymerase inhibitors induces apoptosis in cells deficient in other key DNA repair components ...
Terry J. Gaymes +3 more
doaj +1 more source
NAD+ Degrading Enzymes, Evidence for Roles During Infection
Frontiers in Molecular Biosciences, 2021 Declines in cellular nicotinamide adenine dinucleotide (NAD) contribute to metabolic dysfunction, increase susceptibility to disease, and occur as a result of pathogenic infection.
Arnold Tan, Craig L. Doig
doaj +1 more source
The effect of advanced glycation endproduct accumulation on bone [PDF]
, 2017 Diabetes is associated with increased fracture risk, which leads to increased morbidity and eventual mortality with a substantial financial burden.
Van Vliet, Miranda
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