Results 111 to 120 of about 694,352 (283)
Advanced Materials, EarlyView.ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu +8 more
wiley +1 more source
Egyptian Rheumatology and RehabilitationBackground Systemic lupus erythematosus is a multisystem autoimmune disorder that displays numerous autoantibodies such as anti-nuclear, anti-Smith, anti-double-stranded DNA, and anti-ribosomal antibodies.
Menna N. Hemdan +4 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2007 Virus-infected leaf tissues comprise a heterogeneous mixture of cells at different stages of infection. The spatial and temporal relationships between sites of virus accumulation and the accompanying host responses, such as altered host gene expression ...
Chunling Yang +8 more
doaj +1 more source
Advanced Materials, EarlyView.A pH‐responsive biomaterial interface integrates bactericidal peptides, cell‐recruiting peptides, and magnesium ions into a multifunctional system. Infection‐induced acidification triggers antimicrobial peptide release while cell‐recruiting peptides mobilize bone marrow stem cells.
Zhenyu Li +9 more
wiley +1 more source
Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly
Advanced Science, EarlyView.Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao +5 more
wiley +1 more source
Cancer Biogenesis in Ribosomopathies
Cells, 2019 Ribosomopathies are congenital diseases with defects in ribosome assembly and are characterized by elevated cancer risks. Additionally, somatic mutations in ribosomal proteins have recently been linked to a variety of cancers. Despite a clear correlation
Sergey O. Sulima +2 more
doaj +1 more source
Identification of the prebiotic translation apparatus within the contemporary ribosome [PDF]
, 2009 A structural element that could have existed independently in the prebiotic era was identified at the active site of the contemporary ribosome. It is suggested to have functioned as a proto-ribosome catalyzing peptide bond formation and non-coded ...
Ada Yonath +3 more
core +1 more source
Advanced Science, EarlyView.xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben +4 more
wiley +1 more source
Early Diagnosis of Disseminated Mycobacterium genavense Infection
Emerging Infectious Diseases, 2008 Victoire de Lastours +6 more
doaj +1 more source
Fate of specific ribonucleoside triphosphatases on purification and reconstitution of the ribosomal system of escherichia coli [PDF]
Fate of specific ribonucleoside triphosphatases purification and reconstitution of ribosomal system of Escherichia ...
Fiala, J., Raacke, I. D.
core +1 more source