Results 171 to 180 of about 399,518 (261)
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond +7 more
wiley +2 more sources
Ribosome Biogenesis and Translational Control in Skeletal Muscle Atrophy and Hypertrophy: Mechanisms and Therapeutic Perspectives. [PDF]
Xu M, Liu X.
europepmc +1 more source
Standardized RNA extraction protocol for <i>Entamoeba</i> species: advancing molecular diagnostics and amebiasis control. [PDF]
Cox G +11 more
europepmc +1 more source
Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring. [PDF]
Pradhan S +6 more
europepmc +1 more source
Maternal regulation of translation capacity across generations. [PDF]
Sarinay Cenik E.
europepmc +1 more source
Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
wiley +2 more sources
Differential modulation of gentamicin antibacterial activity by vitamin B12 and vitamin D3 against Gram-positive and Gram-negative bacteria: an <i>in vitro-in silico</i> study. [PDF]
M'hamedi I +5 more
europepmc +1 more source
Es wird eine Strategie zur dualen Modifikation von Peptiden auf der Festphase vorgestellt, die die S‐Alkinylierung von Peptidthiosulfonaten und eine regioselektive, iridiumkatalysierte Azid‐Thioalkin‐Zykloaddition umfasst. Dieses Verfahren ermöglicht zuverlässig den Zugang zu Peptiden mit komplexen, nicht‐kanonischen Modifikationen und ist mit ...
Marius Werner +5 more
wiley +1 more source

