Results 171 to 180 of about 399,518 (261)

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

open access: yesAngewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond   +7 more
wiley   +2 more sources

Standardized RNA extraction protocol for <i>Entamoeba</i> species: advancing molecular diagnostics and amebiasis control. [PDF]

open access: yesFront Cell Infect Microbiol
Cox G   +11 more
europepmc   +1 more source

Bacterial Ribosome

open access: yesBacteriological Reviews, 1970
openaire   +2 more sources

Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring. [PDF]

open access: yesPLoS Biol
Pradhan S   +6 more
europepmc   +1 more source

Structure of the ribosome

open access: yesProgress in Biophysics and Molecular Biology, 1969
openaire   +2 more sources

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

open access: yesAngewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood   +6 more
wiley   +2 more sources

Peptidthioester und Peptidtriazolderivate durch Duale Modifikation von Peptidthiosulfonaten auf dem Harz

open access: yesAngewandte Chemie, EarlyView.
Es wird eine Strategie zur dualen Modifikation von Peptiden auf der Festphase vorgestellt, die die S‐Alkinylierung von Peptidthiosulfonaten und eine regioselektive, iridiumkatalysierte Azid‐Thioalkin‐Zykloaddition umfasst. Dieses Verfahren ermöglicht zuverlässig den Zugang zu Peptiden mit komplexen, nicht‐kanonischen Modifikationen und ist mit ...
Marius Werner   +5 more
wiley   +1 more source

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