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Ribosomal Proteins in Ribosome Assembly [PDF]

open access: yesBiomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
doaj   +5 more sources

Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins [PDF]

open access: yesMolecules, 2016
Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Wei-Wei Shi   +3 more
doaj   +5 more sources

The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral Infection [PDF]

open access: yesBiomolecules
The eukaryotic ribosome is a large ribonucleoprotein complex consisting of four types of ribosomal RNA (rRNA) and approximately 80 ribosomal proteins (RPs), forming the 40S and 60S subunits.
Zhongwei Zhao   +8 more
doaj   +3 more sources

Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Annapina Russo
exaly   +4 more sources

Mitochondrial Ribosomal Proteins and Cancer [PDF]

open access: yesMedicina
Mitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu   +5 more
doaj   +2 more sources

Phylogenomics of prokaryotic ribosomal proteins. [PDF]

open access: yesPLoS ONE, 2012
Archaeal and bacterial ribosomes contain more than 50 proteins, including 34 that are universally conserved in the three domains of cellular life (bacteria, archaea, and eukaryotes).
Natalya Yutin   +3 more
doaj   +5 more sources

Regulation of Ribosomal Proteins on Viral Infection

open access: yesCells, 2019
Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes involved in the cellular process of protein biosynthesis, known as “translation”.
Shuo Li
doaj   +3 more sources

Ribosome specialization in cancer: a spotlight on ribosomal proteins. [PDF]

open access: yesNAR Cancer
AbstractIn the past few decades, our view of ribosomes has changed substantially. Rather than passive machines without significant variability, it is now acknowledged that they are heterogeneous, and have direct regulatory capacity. This ‘ribosome heterogeneity’ comes in many flavors, including in both the RNA and protein components of ribosomes, so ...
Ramalho S, Dopler A, Faller WJ.
europepmc   +3 more sources

Ribosomal proteins in hepatocellular carcinoma: mysterious but promising [PDF]

open access: yesCell & Bioscience
Ribosomal proteins (RPs) are essential components of ribosomes, playing a role not only in ribosome biosynthesis, but also in various extra-ribosomal functions, some of which are implicated in the development of different types of tumors.
Qian Su   +6 more
doaj   +2 more sources

Proteomics shows that brain metastases of lung adenocarcinoma overexpress ribosomal proteins in response to gamma knife radiosurgery [PDF]

open access: yesScientific Reports
Gamma knife radiosurgery (GKRS) is recommended as the first-line treatment for brain metastases of lung adenocarcinoma (LUAD) in many guidelines, but its specific mechanism is unclear.
Luqing Tong   +8 more
doaj   +2 more sources

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