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Ribosomal Proteins in Ribosome Assembly [PDF]
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
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Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins [PDF]
Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Wei-Wei Shi +3 more
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The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral Infection [PDF]
The eukaryotic ribosome is a large ribonucleoprotein complex consisting of four types of ribosomal RNA (rRNA) and approximately 80 ribosomal proteins (RPs), forming the 40S and 60S subunits.
Zhongwei Zhao +8 more
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Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Annapina Russo
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Mitochondrial Ribosomal Proteins and Cancer [PDF]
Mitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu +5 more
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Phylogenomics of prokaryotic ribosomal proteins. [PDF]
Archaeal and bacterial ribosomes contain more than 50 proteins, including 34 that are universally conserved in the three domains of cellular life (bacteria, archaea, and eukaryotes).
Natalya Yutin +3 more
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Regulation of Ribosomal Proteins on Viral Infection
Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes involved in the cellular process of protein biosynthesis, known as “translation”.
Shuo Li
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Ribosome specialization in cancer: a spotlight on ribosomal proteins. [PDF]
AbstractIn the past few decades, our view of ribosomes has changed substantially. Rather than passive machines without significant variability, it is now acknowledged that they are heterogeneous, and have direct regulatory capacity. This ‘ribosome heterogeneity’ comes in many flavors, including in both the RNA and protein components of ribosomes, so ...
Ramalho S, Dopler A, Faller WJ.
europepmc +3 more sources
Ribosomal proteins in hepatocellular carcinoma: mysterious but promising [PDF]
Ribosomal proteins (RPs) are essential components of ribosomes, playing a role not only in ribosome biosynthesis, but also in various extra-ribosomal functions, some of which are implicated in the development of different types of tumors.
Qian Su +6 more
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Proteomics shows that brain metastases of lung adenocarcinoma overexpress ribosomal proteins in response to gamma knife radiosurgery [PDF]
Gamma knife radiosurgery (GKRS) is recommended as the first-line treatment for brain metastases of lung adenocarcinoma (LUAD) in many guidelines, but its specific mechanism is unclear.
Luqing Tong +8 more
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