Results 11 to 20 of about 445,989 (194)
Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins [PDF]
Molecules, 2016 Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Wei-Wei Shi +3 more
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Biomarker Research, 2021 Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
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The Modular Adaptive Ribosome. [PDF]
PLoS ONE, 2016 The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav +5 more
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Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Xiang, Zhou +4 more
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Tagging of RPS9 as a tool for ribosome purification and identification of ribosome-associated proteins [PDF]
Archives of Biological Sciences, 2021 Ribosomes, the catalytic machinery required for protein synthesis, are comprised of 4 ribosomal RNAs and about 80 ribosomal proteins in mammals. Ribosomes further interact with numerous associated factors that regulate their biogenesis and function.
Jovanović Bogdan +3 more
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Ribosome specialization in cancer: a spotlight on ribosomal proteins. [PDF]
NAR CancerAbstractIn the past few decades, our view of ribosomes has changed substantially. Rather than passive machines without significant variability, it is now acknowledged that they are heterogeneous, and have direct regulatory capacity. This ‘ribosome heterogeneity’ comes in many flavors, including in both the RNA and protein components of ribosomes, so ...
Ramalho S, Dopler A, Faller WJ.
europepmc +3 more sources
Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. [PDF]
PLoS ONE, 2013 During the assembly process of ribosomal subunits, their structural components, the ribosomal RNAs (rRNAs) and the ribosomal proteins (r-proteins) have to join together in a highly dynamic and defined manner to enable the efficient formation of ...
Uli Ohmayer +14 more
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Plants, 2023 The target of rapamycin (TOR) protein phosphorylates its downstream effector p70kDa ribosomal protein S6 kinases (S6K1) for ribosome biogenesis and translation initiation in eukaryotes.
Achala Bakshi +6 more
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Cell Reports, 2023 Summary: In mammals, about 99% of mitochondrial proteins are synthesized in the cytosol as precursors that are subsequently imported into the organelle. The mitochondrial health and functions rely on an accurate quality control of these imported proteins.
Julie Lavie +11 more
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A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]
, 2013 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith +6 more
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