Results 21 to 30 of about 441,887 (290)
Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]
Open Biology, 2020 Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
doaj +1 more source
The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Biomarker Research, 2021 Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
doaj +1 more source
Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Xiang, Zhou +4 more
openaire +2 more sources
The Modular Adaptive Ribosome. [PDF]
PLoS ONE, 2016 The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav +5 more
doaj +1 more source
Tagging of RPS9 as a tool for ribosome purification and identification of ribosome-associated proteins [PDF]
Archives of Biological Sciences, 2021 Ribosomes, the catalytic machinery required for protein synthesis, are comprised of 4 ribosomal RNAs and about 80 ribosomal proteins in mammals. Ribosomes further interact with numerous associated factors that regulate their biogenesis and function.
Jovanović Bogdan +3 more
doaj +1 more source
Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. [PDF]
PLoS ONE, 2013 During the assembly process of ribosomal subunits, their structural components, the ribosomal RNAs (rRNAs) and the ribosomal proteins (r-proteins) have to join together in a highly dynamic and defined manner to enable the efficient formation of ...
Uli Ohmayer +14 more
doaj +1 more source
Inter-protein sequence co-evolution predicts known physical interactions in bacterial ribosomes and the trp operon [PDF]
, 2016 Interaction between proteins is a fundamental mechanism that underlies virtually all biological processes. Many important interactions are conserved across a large variety of species.
Feinauer, Christoph +3 more
core +10 more sources
Invariant Distribution of Promoter Activities in Escherichia coli [PDF]
, 2009 Cells need to allocate their limited resources to express a wide range of genes. To understand how Escherichia coli partitions its transcriptional resources between its different promoters, we employ a robotic assay using a comprehensive reporter strain ...
A Zaslaver +40 more
core +8 more sources
Plants, 2023 The target of rapamycin (TOR) protein phosphorylates its downstream effector p70kDa ribosomal protein S6 kinases (S6K1) for ribosome biogenesis and translation initiation in eukaryotes.
Achala Bakshi +6 more
doaj +1 more source
Cell Reports, 2023 Summary: In mammals, about 99% of mitochondrial proteins are synthesized in the cytosol as precursors that are subsequently imported into the organelle. The mitochondrial health and functions rely on an accurate quality control of these imported proteins.
Julie Lavie +11 more
doaj +1 more source