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Hungry Codons Promote Frameshifting in Human Mitochondrial Ribosomes
Science, 2010During translation of mitochondrial genes, shifting the ribosome reading frame avoids unconventional arginine codons.
Temperley R +4 more
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Structural basis of ribosomal frameshifting
2021Versatility in genetic decoding enriches gene expression. Programmed shifting of the reading frame during translation is a prominent feature productively utilized in probably all life forms. While the occurrences, function, and mechanistic components have been identified for many instances of frameshifting, structural understanding of their basis at ...
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A dynamical model of programmed −1 ribosomal frameshifting
Journal of Theoretical Biology, 2013Programmed -1 ribosomal frameshifting is the most widely used translational recoding mechanism of RNA viruses. How the frameshifting occurs at the slippery sequence on the presence of a downstream mRNA pseudoknot has not been fully understood. Here, we present systematical analysis of the -1 frameshifting that can occur during every transition step in ...
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HIV pol Expression via a Ribosomal Frameshift
1990The genetic relationship of the gag and pol genes of all retroviruses is approximately the same and the configuration of the protein products of these genes is also strongly conserved (Figure 1) (Weiss et al., 1982). The gag and pol genes are adjacent at the beginning of retroviral transcriptional unit and in most cases the 3′ end of gag and the 5′ end
Alan J. Kingsman +2 more
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Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome
Science, 2021Pramod R Bhatt +2 more
exaly
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting
Nature, 2023Juan Carlos Yam-Puc +2 more
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