Results 221 to 230 of about 497,148 (303)

Fluctuating Numbers of Ribosomal Genes [PDF]

Nature, 1972
openaire   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, EarlyView.
Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and posttranscriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron splicing ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Multi-tissue analysis identifies mitochondrial genes in chicken aging-induced productivity decline. [PDF]

J Anim Sci Biotechnol
Gao M, Zhang J, Zhang B, Jiang X, Niu B, Zhong C, Lan F, Zhang W, Yang N, Sun C.   +9 more
europepmc   +1 more source

Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz, Anna‐Lena Drommershausen, Alexander Grünberger, Dirk Holtmann   +3 more
wiley   +1 more source

Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns. [PDF]

Elife
Kamei KF, Kobayashi-Kirschvink KJ, Nozoe T, Nakaoka H, Umetani M, Wakamoto Y.   +5 more
europepmc   +1 more source

The Interplay of Dispersion and Thermal Shock in Pseudomonas Aeruginosa Biofilms

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Pathological bacterial biofilms formed on medical implants pose a significant challenge in clinical settings due to their resistance to antibiotics and the host immune response. Eradication of these biofilms by thermal shock has gained increasing attention as a means of eliminating these infections.
Hossein Zare, Josiah Power, Eric Nuxoll
wiley   +1 more source

Evidence for strong purifying selection of human <i>47S</i> ribosomal RNA genes. [PDF]

Proc Natl Acad Sci U S A
Ma X, Chow F, Galbraith B, Sultanov D, Behar EK, Hochwagen A.   +5 more
europepmc   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu, Igor Koop, Gavin Murugan, Thagshanen Thillairajah, Karen M. Polizzi   +4 more
wiley   +1 more source

The complete mitochondrial genome of <i>Cornus officinalis</i> reveals a multipartite structure and clarifies its phylogenetic position. [PDF]

Mitochondrial DNA B Resour
Olutayo MT, Jiang Z, Zhou H, Wang H, Zhang H.   +4 more
europepmc   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

Bulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source