Results 141 to 150 of about 5,829,574 (377)

RNA Polymerase Subunits and Ribosomal Proteins: An Overview and Their Genetic Impact on Complex Human Traits

open access: yesFrontiers in Bioscience-Landmark
Accurate gene expression is fundamental for sustaining life, enabling adaptive responses to routine tasks and management of urgent cellular environments.
Jihye Ryu, Chaeyoung Lee
doaj   +1 more source

Transactivation of programmed ribosomal frameshifting by a viral protein

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2014
Significance Ribosomes synthesize proteins by translating mRNAs into linear chains of amino acids through the decoding of consecutive nucleotide triplets (codons).
Yanhua Li   +13 more
semanticscholar   +1 more source

80S ribosomal proteins [PDF]

open access: yesBiochemical Journal, 1972
O H W Martini   +2 more
openaire   +4 more sources

ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development

open access: yesAdvanced Science, EarlyView.
Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley   +1 more source

Combining multiomics to analyze the molecular mechanism of hair follicle cycle change in cashmere goats from Inner Mongolia

open access: yesFrontiers in Veterinary Science
Sheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep.Inner Mongolia Cashmere Goat is a local excellent breed of cashmere and meat dual-purpose,
Chongyan Zhang   +22 more
doaj   +1 more source

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.

open access: yesBlood, 2011
Haploinsufficiency for ribosomal protein genes has been implicated in the pathophysiology of Diamond-Blackfan anemia (DBA) and the 5q-syndrome, a subtype of myelodysplastic syndrome. The p53 pathway is activated by ribosome dysfunction, but the molecular
S. Dutt   +11 more
semanticscholar   +1 more source

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

open access: yesAdvanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu   +10 more
wiley   +1 more source

When a ribosomal protein grows up – the ribosome assembly path of Rps3

open access: yesMicrobial Cell, 2017
The biogenesis of ribosomes is a central process in all dividing cells. Eukaryotic ribosomes are composed of a large 60S and a small 40S subunit, each comprising a complex assembly of ribosomal RNA (rRNA) and ribosomal proteins (r-proteins).
Brigitte Pertschy
doaj   +1 more source

Slowing translation to avoid ribosome population extinction and maintain stable allocation at slow growth rates [PDF]

open access: yesarXiv
To double the cellular population of ribosomes, a fraction of the active ribosomes is allocated to synthesize ribosomal proteins. Subsequently, these ribosomal proteins enter the ribosome self-assembly process, synthesizing new ribosomes and forming the well-known ribosome autocatalytic subcycle.
arxiv  

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