Results 211 to 220 of about 5,829,574 (377)
Alteration of 5S RNA conformation by ribosomal proteins L18 and L25 [PDF]
, 1977 David G. Bear +3 more
openalex +1 more source
Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides
Angewandte Chemie, EarlyView.The hypothesized convergent biosynthesis of triculamin‐like lasso peptides from different biosynthetic gene cluster (BGC) types represented across multiple bacterial phyla. The elucidation of the triculamin non‐canonical BGC and resistance mechanism by heterologous expression in Streptomyces albus and in vitro acetylation with resistance conveying ...
Aske Merrild +3 more
wiley +2 more sources
Cancer Medicine, Volume 11, Issue 24, Page 5050-5065, December 2022., 2022 The aberrant expression pattern and prognostic implications of HIVEP3 in AML were explored and validated based on versatile bioinformatics tools. A LASSO model which combined HIVEP3 with ferroptosis regulators was created to predict the prognosis for AML patients.
Xiaoning Zhang +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Secondary metabolites (SMs) are essential across all life domains, yet those originating from the Archaea domain remain poorly understood. Here, the systematic genome mining and the pioneering heterologous expression of archaeal SMs have revealed the chemical landscape of archaeal lanthipeptides, showing both canonical and non‐canonical forms.
Zhi‐Man Song +13 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Ein schematischer Überblick über die schädlichen Wirkungen von Ciprofloxacin im Zusammenhang mit mitochondrialer Toxizität. AIFM1 spielt eine Rolle beim MIA40‐vermittelten Import in das IMS und bei der oxidativen Faltung von kernkodierten Proteinen, einschließlich der Untereinheiten der ETC‐Komplexe I und IV.
Till Reinhardt +14 more
wiley +1 more source
Prognosis prediction of stage IV colorectal cancer patients by mRNA transcriptional profile
Cancer Medicine, Volume 11, Issue 24, Page 4900-4912, December 2022., 2022 This study aimed to clarify the prognostic factors for stage IV CRC patients undergoing primary cancer resection but not liver metastasis resection. WES and RNA‐Seq were used to sequence primary cancer tissues of 78 and 84 patients, respectively. Models were established to stratify the prognosis and to predict individual patient prognosis.
Bian Wu +5 more
wiley +1 more source
RNA-RNA interactions in the binding site of protein L24 on 23S ribosomal RNA of E. coli II. Sequence analysis of the interacting fragments [PDF]
, 1978 Alain Krol +3 more
openalex +1 more source
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley +1 more source
Formylmethionyl‐tRNA Binding Properties of Escherichia coli Ribosomal Protein S1 [PDF]
, 1979 Percy T. LI +3 more
openalex +1 more source
Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha‐Tubulins in Human Cells**
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Protein post‐translational modifications allow cells to swiftly adjust activity and localization of proteins. Here, we developed a chemical proteomic approach to determine a protein tyrosination status using an O‐propargyl tyrosine probe. We show that tyrosination modifies previously described alpha‐tubulins with ‐EEY C‐terminal sequence together with ...
Dmytro Makarov, Pavel Kielkowski
wiley +1 more source