Results 231 to 240 of about 334,433 (309)

Pseudotetraivprolide aus Pseudomonas entomophila liefern Einblicke in die Biosynthese von Detoxin/Rimosamid‐ähnlichen Anti‐Antibiotika

Angewandte Chemie, EarlyView.
Pseudotetraivprolid ist ein neuer Akteur unter den Detoxin/Rimosamid‐ähnlichen Naturstoffen. Die Biosynthese erfordert FabD aus dem Primärstoffwechsel und einen PipDFG‐Komplex für die Acetylierung im letzten Schritt – wodurch schließlich die anti‐antibiotische Wirkung entsteht.
Edna Bode, Julia Büllesbach, Kevin Bauer, Yan‐Ni Shi, Simon Reiners, Ziheng Cui, Petra Happel, Yi‐Ming Shi, Kevin Hoffmann, Peter Grün, Bianca Pommerenke, Uli Kazmaier, Martin Grininger, Helge B. Bode   +13 more
wiley   +1 more source

Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides

Angewandte Chemie, EarlyView.
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang, Alexander A. Vinogradov, Yin Sun, Hiroaki Suga   +3 more
wiley   +2 more sources

Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression. [PDF]

iScience
Lorenzo-Martín LF, Robles-Valero J, Ramírez-Cota R, Gaspar SG, Fuentes P, Gentilella A, Bustelo XR, Dosil M.   +7 more
europepmc   +1 more source

Synthesis of ribosomal proteins during growth of Streptomyces coelicolor

, 1994
Gloria Blanco, M. Rosario Rodicio, Anna Maria Puglia, Cármen Méndez, Charles J. Thompson, José A. Salas   +5 more
openalex   +2 more sources

Translation‐Promoting Effects of RNA Template Overhangs in the Absence of Ribosomes

Angewandte Chemie, EarlyView.
Ribosome‐free translation of an RNA sequence into a peptide sequence can be controlled by the folding of the template strand. Overhang sequences forming a triplex structure with the templating region and the peptidoyl RNA in pH‐dependent manner increase yields up to 40‐fold through entropic effects and mixed anhydride formation, allowing for controlled,
Nikolaos Giannakopoulos, Martin Rentschler, Clemens Richert   +2 more
wiley   +2 more sources

Multi-omics analysis reveals CMTR1 upregulation in cancer and roles in ribosomal protein gene expression and tumor growth. [PDF]

Cell Commun Signal
Campeanu IJ, Jiang Y, Afisllari H, Dzinic S, Polin L, Yang ZQ.   +5 more
europepmc   +1 more source

Changes of Ribosomal Protein S3 Immunoreactivity and Its New Expression in Microglia in the Mice Hippocampus After Lipopolysaccharide Treatment

, 2012
Hui‐Young Lee, Joon Ha Park, Choong Hyun Lee, Bingchun Yan, Ji Hyeon Ahn, Young Ju Lee, Chan Woo Park, Jun Hwi Cho, Soo Young Choi, Moo‐Ho Won   +9 more
openalex   +2 more sources

Vielseitiger und selektiver Biomolekül‐Pulldown mit kombinatorischen DNA‐quervernetzten Polymeren

Angewandte Chemie, EarlyView.
Wir stellen ein programmierbares Polymersystem für die universelle, sequenzselektive Bioseparation unter nativen Bedingungen vor. Eine Polymerphasentrennung wird durch kombinatorische DNA‐Vernetzung erreicht, wodurch DNA, RNA oder Proteine in homogener Lösung mit hoher Pulldown‐Effizienz und vernachlässigbarer Hintergrundbindung eingefangen werden ...
Sarah K. Speed, Krishna Gupta, Yu‐Hsuan Peng, Elisha Krieg   +3 more
wiley   +1 more source

Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway. [PDF]

Front Immunol
Li X, Meng W, Wang X, Huang S, Wang J, Liang H, Si D.   +6 more
europepmc   +1 more source

Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility. [PDF]

PLoS Pathog
Greene J, Cotten KL, Snyder RA, Huiszoon RC, Chu S, Braza RED, Chapin AA, Stine JM, Bentley WE, Ghodssi R, Davis KM.   +10 more
europepmc   +1 more source