Results 261 to 270 of about 6,113,563 (357)

Ribosomal protein S1 and polypeptide chain initiation in bacteria.

, 1975
W. Szer, José M. Hermoso, Steven Leffler   +2 more
openalex   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Peptidic Tryptophan Halogenation by a Promiscuous Flavin‐Dependent Enzyme

Angewandte Chemie, EarlyView.
ChlH, a flavin‐dependent tryptophan halogenase, was reconstituted in vitro and capable of modifying a wide array of diverse peptidic substrates. This suggests a potential use in the biocatalytic production of chlorinated peptides. Abstract Amino acids undergo numerous enzymatic modifications.
Andrew J. Rice, Mayuresh G. Gadgil, Paola Bisignano, Richard A. Stein, Hassane S. Mchaourab, Douglas A. Mitchell   +5 more
wiley   +2 more sources

Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression. [PDF]

iScience
Lorenzo-Martín LF, Robles-Valero J, Ramírez-Cota R, Gaspar SG, Fuentes P, Gentilella A, Bustelo XR, Dosil M.   +7 more
europepmc   +1 more source

Replacement of Ribosomal Protein S1 by Interference Factor iα in Ribosomal Binding of Phage MS2 RNA

, 1974
José M. Hermoso, W. Szer
openalex   +1 more source

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

Advanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael, Yuen Ting Lam, Timothy C. Mitchell, Miguel Santos, Alex H. P. Chan, Xinying Liu, Angus J. Grant, Matthew J. Moore, David F. Fletcher, Richard P. Tan, Steven G. Wise   +10 more
wiley   +1 more source

Real‐Time Eco–AI, Electrophoresis‐Correlative Data‐Dependent Acquisition with AI‐Based Data Processing Broadens Access to Single‐Cell Mass Spectrometry Proteomics

Angewandte Chemie, EarlyView.
An affordable single‐cell proteomics workflow combines capillary electrophoresis, real‐time ion sorting, and AI‐aided spectral deconvolution to profile early Xenopus embryonic cells. Despite using a legacy Orbitrap, this strategy matches or exceeds the sensitivity of modern instruments, uncovering proteome dynamics at sub‐nanogram scale.
Bowen Shen, Fei Zhou, Peter Nemes
wiley   +2 more sources

Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway. [PDF]

Front Immunol
Li X, Meng W, Wang X, Huang S, Wang J, Liang H, Si D.   +6 more
europepmc   +1 more source

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Science, 2009
C. Selman, Jennifer M. A. Tullet, Daniela Wieser, E. Irvine, Steven J. Lingard, A. I. Choudhury, M. Claret, Hind Al‐Qassab, D. Carmignac, Faruk Ramadani, A. Woods, I. Robinson, E. Schuster, R. Batterham, S. Kozma, G. Thomas, D. Carling, K. Okkenhaug, J. Thornton, L. Partridge, D. Gems, D. Withers   +21 more
semanticscholar   +1 more source

Cyclochlorotine Hydroxylase CctR Reveals DUF3328 as a Family of Copper‐Dependent Metalloenzymes

Angewandte Chemie, EarlyView.
DUF3328 is an enigmatic enzyme family implicated in diverse transformations in fungal natural product biosynthesis, yet its functions remain largely underexplored. Through biochemical characterization of the cyclochlorotine hydroxylase CctR, we define DUF3328 as a family of copper‐dependent metalloenzymes.
Wentao Huang, Jakob K. Reinhardt, Anru Tian, Xiao Zhang, Binghui Li, Noah Gould, Sashirekha Nallapati, Alexander R. Ivanov, Yi Wang, Jason J. Guo, David E. Budil, Jing‐Ke Weng   +11 more
wiley   +2 more sources