Adaptive remodeling of the bacterial proteome by specific ribosomal modification regulates Pseudomonas infection and niche colonisation [PDF]
, 2016 Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments.
A Brencic +83 more
core +3 more sources
Haematologica, 2014 Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25% of patients.
Pekka Jaako +7 more
doaj +1 more source
The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation
RNA Biology, 2022 The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear export of pre-40S particles to the cytoplasm.
Ingrid Rössler +7 more
doaj +1 more source
Isolation of Ribosomal Particles from the Unicellular Cyanobacterium Synechocystis sp. PCC 6803 [PDF]
, 2017 Isolation of ribosomal particles is an essential step in the study of ribosomal components as well as in the analysis of trans-acting factors that interact with the ribosome to regulate protein synthesis and modulate the expression profile of the cell ...
Galmozzi, Carla V. +1 more
core +1 more source
Ribosomal protein RPL26 is the principal target of UFMylation
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Ubiquitin fold modifier 1 (UFM1) is a ubiquitin-like posttranslational modifier that is essential for tissue development in metazoans. Genetic ablation of UFM1 or the genes that encode the enzymes that conjugate UFM1 to protein targets ...
C. P. Walczak +8 more
semanticscholar +1 more source
A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]
, 2013 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith +6 more
core +2 more sources
Tumor Biology, 2017 Hepatocellular carcinoma is one of the most prevalent neoplasms and the leading cause of cancer-related mortality worldwide. Mitochondrial ribosomal protein S23 is encoded by a nuclear gene and participates in mitochondrial protein translation ...
Meng Pu +9 more
doaj +1 more source
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
Nature Communications, 2019 The majority of patients with neuroblastoma due to MYCN oncogene amplification and consequent N-Myc oncoprotein over-expression die of the disease. Here our analyses of RNA sequencing data identify the long noncoding RNA lncNB1 as one of the transcripts ...
Pei Y. Liu +34 more
semanticscholar +1 more source
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types
OncoTarget, 2017 For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types.
L. Fancello +4 more
semanticscholar +1 more source