Results 291 to 300 of about 6,082,749 (396)

Ubiquitin C‐Terminal Hydrolase L1 (UCHL1), Beyond Hydrolysis

open access: yesBioEssays, EarlyView.
UCHL1 is a neuron‐enriched component of the ubiquitin‐proteasome system. This review debates the biological relevance of its biochemical roles: limited DUB activity, potential ligase function, and mono‐ubiquitin stabilization. We emphasize the need to clarify the mechanisms and identify natural substrates for each function to understand their role in ...
Anwar Bdarneh   +2 more
wiley   +1 more source

Adaptation to zinc restriction in Streptococcus agalactiae: role of the ribosomal protein and zinc-importers regulated by AdcR. [PDF]

open access: yesmSphere
Melet M   +8 more
europepmc   +1 more source

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

open access: yesScience, 2009
C. Selman   +21 more
semanticscholar   +1 more source

Microtiter Plate Cultivation Systems Enable Chemically Diverse Metabolic Footprints During Bacterial Natural Product Discovery

open access: yesBiotechnology and Bioengineering, EarlyView.
The utilization of microtiter plate cultivation systems in the discovery of natural products expands the secondary metabolic footprint. Microtiter plate cultivation systems, in particular the 48 well flower plate, facilitate the parallelization of bacterial cultivation and offer a greater degree of comparability to stirred tank bioreactors in ...
Anton Lindig   +2 more
wiley   +1 more source

Improved Mixing Properties of Stirred Fermentation of an Aspergillus oryzae Hyphal Dispersion Mutant

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The complexity of mechanical and biological processes in filamentous fungal fermentation remains a major obstacle to improving product yield. We previously demonstrated that the AGΔ‐GAGΔ strain of Aspergillus oryzae, lacking both α‐1,3‐glucan (AG) and galactosaminogalactan (GAG), had improved hyphal dispersion, reduced culture viscosity, and ...
Shunya Susukida   +7 more
wiley   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

open access: yesBMEMat, EarlyView.
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian   +6 more
wiley   +1 more source

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