Results 311 to 320 of about 6,159,973 (405)

Transactivation of programmed ribosomal frameshifting by a viral protein

Proceedings of the National Academy of Sciences of the United States of America, 2014
Yanhua Li, E. E. Treffers, S. Napthine, A. Tas, Longchao Zhu, Zhi Sun, S. Bell, B. Mark, P. V. van Veelen, M. V. van Hemert, A. Firth, I. Brierley, E. Snijder, Ying Fang   +13 more
semanticscholar   +1 more source

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Reversible acetylation of ribosomal protein S1 serves as a smart switch for Salmonella to rapidly adapt to host stress. [PDF]

Nucleic Acids Res
Shen YL, Liu TX, Xu L, Ye BC, Zhou Y.
europepmc   +1 more source

Novel Intragenic Duplication of GATAD2B in a Patient With GAND

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The nucleosome remodeling and deacetylation (NuRD) complex is a major chromatin regulator and plays a critical role in regulating gene transcription, genome integrity, and cell cycle progression. Heterozygous variants in GATAD2B, a core NuRD component, have been reported to cause GATAD2B‐Associated Neurodevelopmental Disorder (GAND), an ...
Mari Mori, Steven Estes, Swetha Ramadesikan, Betsy Schmalz, Shayne Plourde, Maria E. Hernandez Gonzalez, Anthony R. Miller, Bimal P. Chaudhari, Richard K. Wilson, Daniel C. Koboldt   +9 more
wiley   +1 more source

Transcription factors induce differential splicing of duplicated ribosomal protein genes during meiosis. [PDF]

Nucleic Acids Res
Petibon C, Catala M, Morales D, Panchapakesan SS, Unrau PJ, Abou Elela S.   +5 more
europepmc   +1 more source

The structure of the RNA binding site of ribosomal proteins S8 and S15.

, 1979
Rachel Müller, R.A. Garrett, Harry F. Noller   +2 more
openalex   +1 more source

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.

Blood, 2011
S. Dutt, A. Narla, Katherine I. Lin, A. Mullally, Nirmalee Abayasekara, Christine Megerdichian, F. H. Wilson, Treeve Currie, A. Khanna-Gupta, N. Berliner, J. Kutok, B. Ebert   +11 more
semanticscholar   +1 more source

De Novo Heterozygous ZFX Frameshift Variant in a Female With an X‐Linked Neurodevelopmental Disorder

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Germline ZFX variants are associated with an X‐linked neurodevelopmental disorder, with 14 males and 16 females reported to date. We describe a 20‐year‐old female with a heterozygous ZFX frameshift variant, p.(Met666Valfs*2), identified by genome sequencing, previously reported in an affected male.
Iftekhar A. Showpnil, Allison Daley, Emily R. Sites, Shayne M. Plourde, Jesse M. Hunter, Dennis W. Bartholomew, April N. Lehman, Daniel C. Koboldt, Rolf W. Stottmann   +8 more
wiley   +1 more source

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

Angewandte Chemie, EarlyView.
In a study of the biosynthesis of the polyether ionophore lysocellin, the P450 enzyme LyoI was found to catalyze a rare oxidation of a hydro‐2,2′‐bifuran moiety to its hemiketal form. The oxidation was identified as the key for unlocking the bioactivity of lysocellin.
Michelle H. Rasmussen, Søren L. B. Møller, Esben B. Svenningsen, Thomas Tørring, Thomas B. Poulsen   +4 more
wiley   +2 more sources

Analogue-Sensitive Inhibition of Histone Demethylases Uncovers Member-Specific Function in Ribosomal Protein Synthesis. [PDF]

J Am Chem Soc
Kuwik J, Scott V, Chedid S, Stransky S, Hinkelman K, Kavoosi S, Calderon M, Watkins S, Sidoli S, Islam K.   +9 more
europepmc   +1 more source