Results 321 to 330 of about 6,082,749 (396)

Total Synthesis of Kanamycins

Chemistry – A European Journal, EarlyView.
This paper reports on creating a novel synthetic route of kanamycins A and B using the desymmetric boron‐mediated aglycon delivery (BMAD) reaction of meso‐diol acceptor with 1,2‐anhydro donor and regio‐ and stereoselective glycosylation of diol acceptor with trichloroacetimidate donor for introduction of a set of challenging 1,2‐cis‐glycosidic linkages
Kanae Hosomi, Banjo Imai, Naoto Takemura, Kazuki Senoo, Chigusa Hayashi, Masayuki Igarashi, Kazunobu Toshima, Daisuke Takahashi   +7 more
wiley   +1 more source

Localized translation and sarcomere maintenance requires ribosomal protein SA in mice. [PDF]

J Clin Invest
Haddad R, Sadeh O, Ziv T, Erlich I, Haimovich-Caspi L, Shemesh A, van der Velden J, Kehat I.   +7 more
europepmc   +1 more source

Tailored Watson–Crick Pairing Partners for Xanthosine in RNA

Chemistry – A European Journal, EarlyView.
RNAs with kappa‐xanthosine (K–X) or 2‐iminocytidine‐xanthosine (2imC–X) base pairs form stable double helices that have higher melting temperatures than those of the A–U or G–U references. Access to these novel 2imC‐modified RNAs is possible through the mild, selective chemical conversion of 2‐thiocytidine RNA precursors.
Stefan Mair, Anna Rázková, Karl Brillet, Catherina Gasser, Eric Ennifar, Ronald Micura   +5 more
wiley   +1 more source

Higher risk of recurrence in early-stage breast cancer patients with increased levels of ribosomal protein S6. [PDF]

Sci Rep
Cascardo F, Vivanco M, Perrone MC, Werbach A, Enrico D, Mando P, Amat M, Martínez-Vazquez P, Burruchaga J, Mac Donnell M, Lanari C, Zwenger A, Waisberg F, Novaro V.   +13 more
europepmc   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

Cytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown, Miguel Ricardo Leung, Tzviya Zeev‐Ben‐Mordehai, Rui Zhang   +3 more
wiley   +1 more source

Keeping it fresh: ribosomal protein SA sustains sarcomeric function via localized translation. [PDF]

J Clin Invest
Nagle A, Regnier M, Davis J.
europepmc   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding of a subset of proteins with alpha helical domains. [PDF]

Nucleic Acids Res
Banerjee A, Ataman M, Smialek MJ, Mookherjee D, Rabl J, Mironov A, Mues L, Enkler L, Coto-Llerena M, Schmidt A, Boehringer D, Piscuoglio S, Spang A, Mittal N, Zavolan M.   +14 more
europepmc   +1 more source

Alteration of a 30S Ribosomal Protein Accompanying the ram Mutation in Escherichia coli

, 1971
Robert A. Zimmermann, Robert T. Garvin, Luigi Gorini   +2 more
openalex   +1 more source

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

Clinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen, Eugène T.P. Verwiel, Maaike van der Lee, Jesse J. Swen, Marcel Santoso, Leiah J. Brigitha, Rick Admiraal, Bastiaan B.J. Tops, Alwin D.R. Huitema, Patrick Kemmeren, Jayne Y. Hehir‐Kwa, Lidwien M. Hanff, Meta H.M. Diekstra   +12 more
wiley   +1 more source