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Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Annapina Russo
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Ribosomal Proteins in the Spotlight
Critical Reviews in Biochemistry and Molecular Biology, 2005The assignment of specific ribosomal functions to individual ribosomal proteins is difficult due to the enormous cooperativity of the ribosome; however, important roles for distinct ribosomal proteins are becoming evident. Although rRNA has a major role in certain aspects of ribosomal function, such as decoding and peptidyl-transferase activity ...
Wilson, D., Nierhaus, K.
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Ribosomal RNA and ribosomal proteins in corynebacteria
Journal of Biotechnology, 2003Ribosomal RNAs (rRNAs) (16S, 23S, 5S) encoded by the rrn operons and ribosomal proteins play a very important role in the formation of ribosomes and in the control of translation. Five copies of the rrn operon were reported by hybridization studies in Brevibacterium (Corynebacterium) lactofermentum but the genome sequence of Corynebacterium glutamicum ...
Juan F, Martín +3 more
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Ribosomal proteins in halobacteria
Canadian Journal of Microbiology, 1989The amino acid sequences of 16 ribosomal proteins from archaebacterium Halobacterium marismortui have been determined by a direct protein chemical method. In addition, amino acid sequences of three proteins, S11, S18, and L25, have been established by DNA sequencing of their genes as well as by protein sequencing.
M, Kimura +4 more
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The Role of Ribosomal Protein Networks in Ribosome Dynamics
Abstract Accurate protein synthesis requires ribosomes to integrate signals from distant functional sites and execute complex dynamics. Despite advances in understanding ribosome structure and function, two key questions remain: how information is transmitted between these distant sites, and how ribosomal movements are synchronized ...
Youri Timsit, Daniel Bennequin
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Functional Dichotomy of Ribosomal Proteins During the Synthesis of Mammalian 40S Ribosomal Subunits [PDF]
Our knowledge of the functions of metazoan ribosomal proteins in ribosome synthesis remains fragmentary. Using siRNAs, we show that knockdown of 31 of the 32 ribosomal proteins of the human 40S subunit (ribosomal protein of the small subunit [RPS ...
Gwennaele Fichant +2 more
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Protein folding on the ribosome
Current Opinion in Structural Biology, 2010In living systems, polypeptide chains are synthesised on ribosomes, molecular machines composed of over 50 protein and nucleic acid molecules. As nascent chains emerge from the ribosomal exit tunnel and into the cellular environment, the majority must fold into specific structures in order to function.
Lisa D, Cabrita +2 more
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Ribosome-inactivating proteins
Toxicon, 1997Abstract Ribosome-inactivating proteins (RIPs, review by Barbieri et a/. 1993) are a class of proteins present in various tissues of several plants which inactivate mammalian ribosomes and, with less activity and to variable extent, plant, fungal, and bacterial ribosomes. They are enzymes, N-glycosidases, which release adenine from rRNA.
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Ribosomes, ribosomal subunits and ribosomal proteins of Lactococcus lactis IL1403
Biochimie, 1992Abstract The preparation of ribosomes and ribosomal subunits of Lactococcus lactis and the characterization of the proteins of the subunits by one- and two-dimensional polyacrylamide gel electrophoresis and ion exchange chromatography are described.
N, Limas Nzouzi, M F, Guerin, D H, Hayes
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