Results 261 to 270 of about 6,145,189 (363)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

METTL3 alters capping enzyme expression and its activity on ribosomal proteins. [PDF]

Sci Rep
Del Valle-Morales D, Romano G, Nigita G, Saviana M, La Ferlita A, Le P, Brown R, Micalo L, Li H, Nana-Sinkam P, Acunzo M.   +10 more
europepmc   +1 more source

Ribosomal proteins as novel players in tumorigenesis

Cancer Metastasis Review, 2013
A. Heras-Rubio, Laura Perucho, Rosana Paciucci, J. Vilardell, M. Lleonart   +4 more
semanticscholar   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions. [PDF]

Elife
Tutak K, Broniarek I, Zielezinski A, Niewiadomska D, Skrzypczak T, Baud A, Sobczak K.   +6 more
europepmc   +1 more source

Synthesis of ribosomal proteins during growth of Streptomyces coelicolor

, 1994
Gloria Blanco, M. Rosario Rodicio, Anna Maria Puglia, Cármen Méndez, Charles J. Thompson, José A. Salas   +5 more
openalex   +2 more sources

Kinetoplast DNA-encoded ribosomal protein S12 [PDF]

, 2013
Inna Aphasizheva, Dmitri Maslov, Ruslan Aphasizhev   +2 more
openalex   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress

Proceedings of the National Academy of Sciences of the United States of America, 2012
Slađana Bursać, Maja Cokarić Brdovčak, M. Pfannkuchen, Ines Oršolić, L. Golomb, Yan Zhu, C. Katz, Lilyn Daftuar, Kristina Grabušić, I. Vukelic, Vedrana Filić, M. Oren, C. Prives, S. Volarević   +13 more
semanticscholar   +1 more source

A single-headed dimer of Escherichia coli ribosomal protein L7/L12 supports protein synthesis

, 1998
Andrew V. Oleinikov, George G. Jokhadze, Robert R. Traut   +2 more
openalex   +2 more sources