Results 201 to 210 of about 1,591,440 (405)

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Recognition of ribosomal RNA sites in DNA. II. The HeLa cell system.

, 1965
Giuseppe Attardi, Po‐Chao Huang, Susan Kabat   +2 more
openalex   +1 more source

Ribosomal RNA Gene

Definitions, 2020

semanticscholar   +1 more source

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science, EarlyView.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
wiley   +1 more source

Specific Inactivation of 16S Ribosomal RNA Induced by Colicin E3 In Vivo [PDF]

, 1971
Catherine M. Bowman, J E Dahlberg, Toshimichi Ikemura, J Konisky, Michio Nomura   +4 more
openalex   +1 more source

N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation

Nature Chemical Biology, 2018
Honghui Ma, Honghui Ma, Honghui Ma, Xiaoyun Wang, Jia-Bing Cai, Qing Dai, Qing Dai, S. K. Natchiar, Ruitu Lv, Kai Chen, Kai Chen, Zhike Lu, Zhike Lu, Hao Chen, Y. Shi, Y. Shi, F. Lan, Jia Fan, B. Klaholz, Tao Pan, Yang Shi, Yang Shi, Chuan He, Chuan He   +23 more
semanticscholar   +1 more source

Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases

Advanced Science, EarlyView.
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang, Sen Yang, Xiaomi Wang, Yuanwei Zhang, Yao Zhao, Menghuan Tao, Jinyi Zhu, Wanxin Zhang, Yansu Wang, Kaixuan Duan, Yan Wang, Wenwu Ye, Zhenfei Guo, Yuanchao Wang   +13 more
wiley   +1 more source

SELECTIVE INHIBITION OF SYNTHESIS OF RIBOSOMAL RNA IN ESCHERICHIA COLI BY LEVORPHANOL

, 1964
Eric J. Simon, Dina Van Praag
openalex   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Metastable secondary structures in ribosomal RNA: A new method for analyzing the titration behavior of rRNA

, 1973
Arnold Revzin, Eberhard Neumann, Aharon Katchalsky   +2 more
openalex   +2 more sources