Results 251 to 260 of about 509,011 (342)

T‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis

open access: yesAdvanced Science, EarlyView.
T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu   +19 more
wiley   +1 more source

The structure of the RNA binding site of ribosomal proteins S8 and S15.

open access: hybrid, 1979
Rachel Müller   +2 more
openalex   +1 more source

Bimetal‐Phenolic Framework to Combat Bacterial Infections via Synergistic Biofilm Dispersal, Bacterial Killing and Immune Modulation

open access: yesAdvanced Science, EarlyView.
A bimetal‐phenolic framework (Que‐Fe‐CeMPF) is developed by direct self‐assembly through the coordination of Fe3+ and Ce4+ with quercetin. Que‐Fe‐CeMPF exhibits multimodal activity, including cleaving matrix eDNA within biofilm, generating hydroxyl radicals via catalytic H2O2 to kill bacteria, and alleviating inflammation by stimulating macrophage ...
Yaran Wang   +9 more
wiley   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

open access: yesAdvanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang   +17 more
wiley   +1 more source

The efficacy and accuracy of ribosomal RNA depletion methods

open access: yes
Ahmed M   +4 more
europepmc   +1 more source

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

open access: yesAdvanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li   +10 more
wiley   +1 more source

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki   +9 more
wiley   +1 more source

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