Results 181 to 190 of about 254,623 (219)
Some of the next articles are maybe not open access.
Trends in Biochemical Sciences, 2005
Fifty years is a long time. In 1955 – the year IUB (later renamed IUBMB) was established – it was known that protein synthesis is associated with ribonucleoprotein particles, which are abundant in cytoplasm, and that the small RNAs – now called tRNAs – are also involved, but no one knew what a ‘ribosome’ was because the word had not yet been coined [1].
Thomas A. Steitz +2 more
openaire +2 more sources
Fifty years is a long time. In 1955 – the year IUB (later renamed IUBMB) was established – it was known that protein synthesis is associated with ribonucleoprotein particles, which are abundant in cytoplasm, and that the small RNAs – now called tRNAs – are also involved, but no one knew what a ‘ribosome’ was because the word had not yet been coined [1].
Thomas A. Steitz +2 more
openaire +2 more sources
Annual Review of Biochemistry, 1997
The ribosome is a large multifunctional complex composed of both RNA and proteins. Biophysical methods are yielding low-resolution structures of the overall architecture of ribosomes, and high-resolution structures of individual proteins and segments of rRNA.
Rachel Green, Harry F. Noller
openaire +3 more sources
The ribosome is a large multifunctional complex composed of both RNA and proteins. Biophysical methods are yielding low-resolution structures of the overall architecture of ribosomes, and high-resolution structures of individual proteins and segments of rRNA.
Rachel Green, Harry F. Noller
openaire +3 more sources
Biochimie, 1991
Abstract Recent advances in the molecular and genetic studies of mitoribosomes especially on the molecular components of the mitoribosome in yeast Saccharomyces cerevisiae which have been investigated in detail in several laboratories, are reviewed.
K. Isono, M. Kitakawa
openaire +2 more sources
Abstract Recent advances in the molecular and genetic studies of mitoribosomes especially on the molecular components of the mitoribosome in yeast Saccharomyces cerevisiae which have been investigated in detail in several laboratories, are reviewed.
K. Isono, M. Kitakawa
openaire +2 more sources
2014
Ribosomes are fundamental components of the cell that are essential for its growth and proliferation. It is hard to imagine that such a fundamental physiological machinery, as ribosomes, does not participate in cancer biology. However, surprisingly, there is a lack of studies towards the role of ribosomal alterations in cancer. Here, we will attempt to
Ricciardi S, Loreni F
openaire +1 more source
Ribosomes are fundamental components of the cell that are essential for its growth and proliferation. It is hard to imagine that such a fundamental physiological machinery, as ribosomes, does not participate in cancer biology. However, surprisingly, there is a lack of studies towards the role of ribosomal alterations in cancer. Here, we will attempt to
Ricciardi S, Loreni F
openaire +1 more source
Journal of Cellular Physiology, 1969
Functionally active 30S ribosomes can be reconstituted in vitro from 16S RNA and a mixture of 30S ribosomal proteins under certain defined conditions. Our previous studies on the specificity and kinetics of reconstitution are summarized and discussed. The reconstitution reaction is first-order with respect to formation of active 30S ribosomes. The rate-
H. Nashimoto +3 more
openaire +3 more sources
Functionally active 30S ribosomes can be reconstituted in vitro from 16S RNA and a mixture of 30S ribosomal proteins under certain defined conditions. Our previous studies on the specificity and kinetics of reconstitution are summarized and discussed. The reconstitution reaction is first-order with respect to formation of active 30S ribosomes. The rate-
H. Nashimoto +3 more
openaire +3 more sources
Nature, 1988
Fashions come and go in biochemistry. The discovery that some RNAs are enzymes is reviving interest in the long-neglected ribosome.
openaire +3 more sources
Fashions come and go in biochemistry. The discovery that some RNAs are enzymes is reviving interest in the long-neglected ribosome.
openaire +3 more sources
Radioimmunoassay for ribosomes
Analytical Biochemistry, 1972Abstract A radioimmunoassay for quantitating ribosomes is presented. The assay allows for precise, efficient, and rapid estimation of ribosomes in small samples of tissue (50–100 mg).
openaire +3 more sources
New England Journal of Medicine, 1967
SEVERAL of the preceding Seminars in Medicine of the Beth Israel Hospital have exemplified the fact that during the past decade medicine has advanced from a firm foundation of morphology and physio...
openaire +3 more sources
SEVERAL of the preceding Seminars in Medicine of the Beth Israel Hospital have exemplified the fact that during the past decade medicine has advanced from a firm foundation of morphology and physio...
openaire +3 more sources
2018
Wnt proteins are secreted glycoproteins that activate different intracellular signal transduction pathways. They regulate cell proliferation and are required for proper embryonic development. Misregulation of Wnt signaling can result in various diseases including cancer.
Michael Kühl, Astrid S. Pfister
openaire +3 more sources
Wnt proteins are secreted glycoproteins that activate different intracellular signal transduction pathways. They regulate cell proliferation and are required for proper embryonic development. Misregulation of Wnt signaling can result in various diseases including cancer.
Michael Kühl, Astrid S. Pfister
openaire +3 more sources
Gerontology, 1979
A recent review of Orgel's hypothesis by Kirkwood is considered in context of what is known about ribosomes.
openaire +3 more sources
A recent review of Orgel's hypothesis by Kirkwood is considered in context of what is known about ribosomes.
openaire +3 more sources