Results 191 to 200 of about 300,260 (284)

Modulation of Gut Microbiota by Protein‐Oligosaccharide Maillard‐Reaction‐Derived Probiotic Microcapsules

Food Bioengineering, EarlyView.
Development of a novel synbiotic microcapsule and its impact on gut microbiota. ABSTRACT As a new type of prebiotic, the Maillard reaction products of protein ‐ oligosaccharide conjugates have emerged as a promising material for probiotic encapsulation and improve host health.
Hongxing Zhang, Yue Shen, Wanting Huang, Xinyi Fang, Yanlin Wang, Xingyuan Ma, Wenyun Zheng   +6 more
wiley   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

Glia, EarlyView.
Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis, Vishwanath V. Prabhu, Bruce D. Carter   +2 more
wiley   +1 more source

Thermodynamically consistent, reduced models of gene regulatory networks. [PDF]

R Soc Open Sci
Pan M, Gawthrop PJ, Faria M, Johnston ST.   +3 more
europepmc   +1 more source

Structure of the hepatitis C virus IRES bound to the human 80S ribosome: Remodeling of the HCV IRES [PDF]

, 2005
Boehringer, D., Lewis, J., Ostareck-Lederer, A., Stark, H., Thermann, R.   +4 more
core  

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

Glia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz, Madison Doceti, JaQuinta Thomas, Abigayle Duffy, Morgan Coburn, Akhabue K. Okojie, Audrey Lee, Elizabeth Aidita Sou, Alban Gaultier, Ukpong B. Eyo   +9 more
wiley   +1 more source

Translational reprogramming under heat stress: a plant's perspective. [PDF]

R Soc Open Sci
Smith M, Taqrir Akramin A, Balcerowicz M.   +2 more
europepmc   +1 more source

Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs

iMetaOmics, EarlyView.
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang, Yanan Xu, Kun Pang, Changhong Wu, Chenxu Zhao, Tong Lei, Jiayu Zhang, Tang Hai, Fangqing Zhao, Yong Zhao   +9 more
wiley   +1 more source

VIRMA-mediated m⁶A modification regulates forebrain formation through modulating ribosome biogenesis. [PDF]

Sci Adv
Wu M, Wu X, Sun H, Wang W, Zhang L, Liu X, Zhang Y, Zhang X, Liu J, Shen B, Zhou T.   +10 more
europepmc   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Advances in ribosome profiling technologies. [PDF]

Biochem Soc Trans
Tomuro K, Iwasaki S.
europepmc   +1 more source