Results 91 to 100 of about 35,431,844 (244)

The Sambucus nigra type-2 ribosome-inactivating protein SNA-I ' exhibits in planta antiviral activity in transgenic tobacco. [PDF]

, 2002
Transgenic tobacco (Samsun NN) plants transformed with a cDNA clone encoding SNA-I′ from Sambucus nigra synthesize, and correctly process and assemble, a fully active type-2 ribosome-inactivating protein. Expression of SNA-I′ under the control of the 35S
Van Damme, Els, Peumans, Willy J, Chen, Ying, CHEN, Y, Van Damme, Els J.M, PEUMANS, WJ   +5 more
core   +1 more source

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

mLife, EarlyView.
Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and intracellular regulatory pathways, with limited attention to the ...
Jing Zhao, Yixiao Xiong, Hongxia Zhao, Jin Wang, Xiaona Fang   +4 more
wiley   +1 more source

BIOACTIVITIES OF SoRIP1, A TYPE 1 RIBOSOME INACTIVATING PROTEIN FROM SPINACIA OLERACEA

Abstract A single-stranded ribosome inactivating protein SoRIP1 from Spinacia oleracea (Spinach) is a 30 kDa protein. It is a multipurpose protein with versatile biological activities. This paper defines cloning and expression of SoRIP1 in bacteria to study its versatile biological properties and cytotoxic potential.
PAKEEZA ISMAIL, Dr. ALEENA SUMRIN
openaire   +2 more sources

Studies on ribosome-inactivating proteins from momordica charantia. [PDF]

, 1997
by Tse Man Fai.Thesis (M.Phil.)--Chinese University of Hong Kong, 1997.Includes bibliographical references (leaves 74-81).ACKNOWLEDGMENTS --- p.IABSTRACT --- p.IILIST OF ABBREVIATIONS --- p.IIITABLE OF CONTENTS --- p.1Chapter CHAPTER 1 ...

core  

Advances in research on autophagy in the maintenance of insect–microbe symbiosis

New Plant Protection, EarlyView.
Autophagy plays a dual regulatory role in insect–microbe symbiotic relationships. Beneficial symbiotic bacteria in insects participate in nutrient exchange via the TOR pathway, whereas pathogenic microbes induce immune defense through the AMPK pathway. Autophagy‐related genes regulate development and pathogen clearance during this process.
Yanbin Wang, Yuqiong Hao, Ke Chen, Hongbin Zhang, Xiansheng Xie, Feirong Ren   +5 more
wiley   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Supervised Protein Structure Classification Using Topological Persistence With DeltaFold

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Recent advances in protein structure prediction have considerably increased the number of available structures, underscoring the need for scalable and accurate methods to compare and classify this huge amount of data. Current approaches based on sequence alignment or structural superposition often lack sensitivity and/or are computationally ...
Joseph Nardin‐Gennequin, Gabriela Ciuperca, Céline Brochier‐Armanet, Philippe Malbos   +3 more
wiley   +1 more source

Gypsophilin, a New Type 1 Ribosome-inactivating Protein fromGypsophila elegans: Purification, Enzymatic Characterization, and Subcellular Localization

Bioscience, Biotechnology, and Biochemistry, 1997
Gypsophila elegans contains a new type 1 ribosome-inactivating protein, which we named gypsophilin. The protein was purified to apparent homogeneity by (NH4)2SO4 fractionation, ion-exchange chromatography, and adsorption chromatography. The protein was found to have a molecular mass of 28.0 kDa and a pI of about 10.1.
YOSHINARI, Shigeo, KORESAWA, Shigehiro, YOKOTA, Sadaki, SAWAMOTO, Hiroshi, TAMURA, Minoru, ENDO, Yaeta   +5 more
openaire   +2 more sources

Elderberry (Sambucus nigra) contains truncated Neu5Ac(α-2,6)Gal/GalNAc-binding type 2 ribosome-inactivating proteins [PDF]

, 1998
Analysis of affinity-purified preparations of the fetuin-binding proteins from elderberry bark and fruits revealed besides the previously reported Neu5Ac(α-2,6)Gal/GalNAc-specific type 2 ribosome-inactivating proteins (RIP) the occurrence of single chain
Barre, Annick, Soma Roy, van Leuven, Fred, Els J.M van Damme, Peumans, Willy J, Fred van Leuven, Rouge, Pierre, Annick Barre, Pierre Rouge, van Damme, Els J.M, Roy, Soma, Willy J Peumans   +11 more
core   +1 more source

Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7

Yeast, EarlyView.
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley   +1 more source