Results 41 to 50 of about 31,654 (255)
Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. [PDF]
, 2014 Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo ...
CHEUNG, HP +13 more
core +3 more sources
FEBS Letters, 1992 A single chain ribosome‐inactivating protein with RNA N‐glycosidase activity, here named Dianthin 29, was isolated from leaves of Dianthus barbatus L. Incubation of intact Escherichia coli ribosomes with Dianthin 29 and subsequent aniline treatment of the isolated rRNA releases a rRNA fragment of 243 nucleotides from 23 S rRNA.
Prestle, Jürgen +3 more
openaire +2 more sources
Preparation of an antitumor and antivirus agent: chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol [PDF]
, 2012 Background: Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. However, strong immunogenicity and
Li, Juan +4 more
core +1 more source
Lectin domains at the frontiers of plant defense [PDF]
, 2014 Plants are under constant attack from pathogens and herbivorous insects. To protect and defend themselves, plants evolved a multi-layered surveillance system, known as the innate immune system.
Lannoo, Nausicaä, Van Damme, Els
core +2 more sources
Frontiers in Pharmacology, 2020 Riproximin (Rpx) is a type II ribosome-inactivating protein with specific anti-proliferative activity. It was purified from Ximenia americana by affinity chromatography using a resin coupled with lactosyl residues.
Micah N. Sagini +6 more
doaj +1 more source
Involvement of loops 2 and 3 of alpha-sarcin on its ribotoxic activity [PDF]
, 2015 Ribotoxins are a family of fungal ribosome-inactivating proteins displaying highly specific ribonucleolytic activity against the sarcin/ricin loop (SRL) of the larger rRNA, with a-sarcin as its best-characterized member.
Castaño Rodríguez, Carlos +7 more
core +1 more source
Bouganin, an Attractive Weapon for Immunotoxins
Toxins, 2018 Bougainvillea (Bougainvillea spectabilis Willd.) is a plant widely used in folk medicine and many extracts from different tissues of this plant have been employed against several pathologies.
Massimo Bortolotti +2 more
doaj +1 more source
British Journal of Cancer, 1997 The present paper describes two immunoconjugates consisting of an anti-epidermal growth factor receptor (EGFR) monoclonal antibody (MAb), named Mint5, covalently linked to the type 1 ribosome-inactivating proteins (RIPs) ocymoidine (Ocy) and pyramidatine
A. Massimo +9 more
semanticscholar +1 more source
Structure and Activity of a Cytosolic Ribosome-Inactivating Protein from Rice
Toxins, 2019 Ribosome-inactivating proteins (RIPs) are cytotoxic enzymes that inhibit protein translation by depurinating ribosomal RNA. Although most plant RIPs are synthesized with leader sequences that sequester them away from the host ribosomes, several RIPs from
Jeroen De Zaeytijd +3 more
doaj +1 more source
, 2008 We studied the in vitro and in planta antiviral activity of the PhRIP I, a type 1 Ribosome-Inactivating Protein originally purified from leaves of the Phytolacca heterotepala.
ANTIMO DI MARO +6 more
core +1 more source