Results 201 to 210 of about 105,196 (322)

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self‐Organizing Biosystems via Amyloid Formation

open access: yesChemistry – A European Journal, Accepted Article.
Short amyloidogenic oligopeptides (APRs) are proposed as early macromolecules capable of forming solvent‐separated nanosystems under prebiotic conditions. This study provides experimental evidence that APRs, such as the aggregation‐prone oligopeptide A (APR‐A), can undergo mutational transitions to form distinct variants, and convert to APR‐B, either ...
Fruzsina Bencs   +7 more
wiley   +1 more source

Impacts of ribosomal RNA sequence variation on gene expression and phenotype. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci
Welfer GA   +9 more
europepmc   +1 more source

Ribosome‐Catalyzed Peptidyl Transfer [PDF]

open access: bronze, 1968
B.E.H. Maden, R.E. Monro
openalex   +1 more source

Total Synthesis of Kanamycins

open access: yesChemistry – A European Journal, Accepted Article.
Structurally‐modified aminoglycosides, such as kanamycin, have shown promise as antibiotics and premature termination codon read‐through drugs to fight against drug‐resistant bacteria and to treat genetic diseases, respectively. Therefore, research on developing and discovering aminoglycoside antibiotics has recently increased.
Kanae Hosomi   +7 more
wiley   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

open access: yesCytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown   +3 more
wiley   +1 more source

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