Results 221 to 230 of about 254,640 (401)

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Translation landscape of stress granules. [PDF]

Sci Adv
Wu Y, Wang X, Meng L, Liao Z, Ji W, Zhang P, Lin J, Guo Q.   +7 more
europepmc   +1 more source

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, EarlyView.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

Sequence‐Specific Installation of Aryl Groups in RNA via DNA‐Catalyst Conjugates

Angewandte Chemie, EarlyView.
DNA oligonucleotides carrying amine nucleophilic catalysts are employed to deliver aryl groups to complementary sites in RNA under physiological conditions. The strategy can be used to sequence‐specifically label protein‐coding RNAs, or to knock down expression selectively, with potential applications in basic transcriptome research and in future ...
Sumon Pratihar, Wenrui Zhong, Sheng Feng, Sayantan Chatterjee, Eric T. Kool   +4 more
wiley   +2 more sources

Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes

, 1969
Sidney Pestka
openalex   +1 more source

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

Animal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source

A rapid, simple, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies. [PDF]

Nat Commun
Erath J, Kemper D, Mugo E, Jacoby A, Valenzuela E, Jungers CF, Beatty WL, Hashem Y, Jovanovic M, Djuranovic S, Pavlovic Djuranovic S.   +10 more
europepmc   +1 more source

Studies on Aminoacyl Transfer from Soluble Ribonucleic Acid to Ribosomes

, 1963
June M. Fessenden, Kivie Moldave
openalex   +1 more source

RIBOSOME PRECURSOR PARTICLES IN NUCLEOLI [PDF]

, 1969
Ming C. Liau, Robert P. Perry
openalex   +1 more source

Mitochondrial ribosomes [PDF]

FEBS Letters, 1971
Borst, P., Grivell, L.A.
openaire   +2 more sources