Results 251 to 260 of about 179,543 (360)

Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD. [PDF]

Sci Adv
Yudin D, Jaskolowski M, Fan Z, Burg N, Chandrasekar S, Lentzsch AM, Scaiola A, Bothe A, Deuerling E, Gamerdinger M, Shan SO, Ban N.   +11 more
europepmc   +1 more source

Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation

Science, 2010
C. MacLennan, J. Gilchrist, M. Gordon, A. Cunningham, M. Cobbold, M. Goodall, R. Kingsley, J. V. Oosterhout, C. Msefula, W. Mandala, Denisse L. Leyton, J. Marshall, E. Gondwe, S. Bobat, R. Doffinger, E. Zijlstra, G. Dougan, M. Drayson, I. Maclennan, M. Molyneux   +19 more
semanticscholar   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source

Time‐dependent effects of transcription‐ and translation‐halting drugs on the spatial distributions of the Escherichia coli chromosome and ribosomes

Molecular Microbiology, 2014
Somenath Bakshi, Heejun Choi, Jagannath Mondal, J. Weisshaar   +3 more
semanticscholar   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity. [PDF]

Cell Rep
Lamb TM, Castillo KD, Porter R, Wu C, Purvine SO, Best G, Zink E, Preh EO, Shen L, Sachs MS, Bell-Pedersen D.   +10 more
europepmc   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Availability of Charged tRNAs Drives Maximal Protein Synthesis at Intermediate Levels of Codon Usage Bias. [PDF]

Bull Math Biol
Hill AM, To K, Wilke CO.
europepmc   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Structural basis for co-translational assembly of homo-oligomeric proteins

Koubek J, Filbeck S, Kopetschke S, Schmitt J, Pfeffer S, Kramer G, Bukau B.   +6 more
europepmc   +1 more source