Results 251 to 260 of about 184,288 (339)
Gene Expression Depends on the Interplay Among Growth, Resource Biogenesis, and Nutrient Quality. [PDF]
Kim J+10 more
europepmc +1 more source
Properties of Membrane-bound Ribosomes in Reticulocytes
W. Schreml, Edward R. Burka
openalex +1 more source
We have shed light on the mode of action behind the postbiotic form of Bifidobacterium breve NCC 2950. Heat treatment of this strain at 90°C leads to the production of 4‐oxo‐2‐pentenoic acid (OPA), which activates NRF2 host response, improving oxidative stress resistance and decreasing inflammation. ABSTRACT Postbiotics are defined as a “preparation of
Francis Foata+11 more
wiley +1 more source
A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics. [PDF]
Baniulyte G, Wade JT.
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella+6 more
wiley +1 more source
Distant ribose 2'-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface. [PDF]
Nandi S+4 more
europepmc +1 more source
ABSTRACT Multiple myeloma (MM) remains incurable; gaps in our understanding of MM molecular pathogenesis and drugs’ resistance mechanisms are involved in the failure of therapies. This study aims to identify proteins significantly impacting MM patients’ response to commonly used therapeutic regimens.
Foteini Paradeisi+14 more
wiley +1 more source
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler+7 more
wiley +1 more source
Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells. [PDF]
Helena-Bueno K+9 more
europepmc +1 more source