Results 241 to 250 of about 28,198 (287)
Protocell Effects on RNA Folding, Function, and Evolution. [PDF]
Acc Chem ResSaha R, Choi JA, Chen IA.
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Efficient circularization of protein-encoding RNAs via a novel cis-splicing system. [PDF]
Nucleic Acids ResQi S +5 more
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Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness. [PDF]
Nat CommunKenchel J +10 more
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CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris. [PDF]
Synth Syst BiotechnolChen K +9 more
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Biopolymers, 1999 The hammerhead ribozyme is an intriguing RNA molecule with the ability to serve as a catalyst to cleave sequence-specifically RNA molecules in an intermolecular reaction. Preferentially Mg(2+) is required for optimal activity by inducing the catalytically competent conformation and by possibly acting as an acid-base catalyst.
Fritz Eckstein, Birgit Bramlage
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Ribozyme-Catalyzed Transcription of an Active Ribozyme
Science, 2011A functional RNA has been synthesized by an RNA enzyme from mononucleotide building blocks.
James Attwater +3 more
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Biochemical Society Transactions, 2002
The hammerhead ribozyme is a small RNA motif consisting of three helices that intersect at a conserved core. When correctly folded, the hammerhead ribozyme stimulates nearly complete cleavage of the phosphodiester chain at a defined internal site to give 2′,3′-cyclic and 5′-hydroxy termini. The cleavage rate is approx.
Olke C. Uhlenbeck, Kenneth F. Blount
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The hammerhead ribozyme is a small RNA motif consisting of three helices that intersect at a conserved core. When correctly folded, the hammerhead ribozyme stimulates nearly complete cleavage of the phosphodiester chain at a defined internal site to give 2′,3′-cyclic and 5′-hydroxy termini. The cleavage rate is approx.
Olke C. Uhlenbeck, Kenneth F. Blount
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Science, 1997
Robertson, Michael P. Bull, Jim On p. [614][1] of this issue, Wright and Joyce report the successful evolution of a catalytic ribozyme selected for its ability to perform ligation. In their Perspective, Ellington et al . comment on the advances in this study over previous efforts and what this work tells us about evolution.
Andrew D. Ellington +2 more
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Robertson, Michael P. Bull, Jim On p. [614][1] of this issue, Wright and Joyce report the successful evolution of a catalytic ribozyme selected for its ability to perform ligation. In their Perspective, Ellington et al . comment on the advances in this study over previous efforts and what this work tells us about evolution.
Andrew D. Ellington +2 more
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ACS Synthetic Biology, 2018
Bacillus subtilis is a typical industrial microorganism and is widely used in industrial biotechnology, particularly for nutraceutical production. There are many studies on the static metabolic engineering of B. subtilis, whereas there are few reports on
Tengfei Niu +6 more
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Bacillus subtilis is a typical industrial microorganism and is widely used in industrial biotechnology, particularly for nutraceutical production. There are many studies on the static metabolic engineering of B. subtilis, whereas there are few reports on
Tengfei Niu +6 more
semanticscholar +1 more source
Ribozymes: the hairpin and Varkud ribozymes are related.
Rivista di biologia, 2003The hairpin ribozyme of plant virusoids and the Varkud ribozyme from a retroplasmid of fungal mitochondria show notable similarities in sequence and secondary structure. Some more distant inter-relationships appear to exist between this pair, the viroid/virusoid hammerhead and the hepatitis delta ribozyme.
David Elder, Ray J. Harris
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