Results 111 to 120 of about 99,315 (292)
Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye+13 more
wiley +1 more source
Diatoms have delicate and complex shells showing different lightweight design principles that have already been applied to technical products improving the mechanical properties.
Simone Andresen+4 more
doaj +1 more source
CRANIOTABES AND BEADING OF THE RIBS AS SIGNS OF RACHITIS [PDF]
HERMAN SCHWARZ
openalex +1 more source
BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou+8 more
wiley +1 more source
This case report is unique due to the rare combination of a history of no trauma and a history of scoliosis correction surgery with instrumentation performed 1 year before presentation.
Fahad Abuguyan
doaj +1 more source
Cryptococcal osteomyelitis in the ribs
Isolated cryptococcal osteomyelitis, in an immunocompetent, is rare and only a few cases have been reported in literature. We present the case of a 30-year-old man presented with pain on the left side of chest with fever and gradually increasing swelling in left lateral lower aspect of chest. Investigation revealed a lytic lesion in the anterior end of
openaire +5 more sources
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li+5 more
wiley +1 more source
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng+9 more
wiley +1 more source