Results 81 to 90 of about 3,312 (222)

Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes

open access: yesExperimental Physiology, EarlyView.
Abstract The pre‐hearing mouse cochlea undergoes critical periods of spontaneous Ca2+‐dependent activity that spreads across non‐sensory supporting cells and inner hair cells (IHCs). These signals have been shown to regulate not only the refinement of neural circuits along the auditory pathway towards functional maturity, but also the maturation of the
Francesca De Faveri   +2 more
wiley   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic   +9 more
wiley   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger   +4 more
wiley   +1 more source

Dark energy and dark matter configurations for wormholes and solitionic hierarchies of nonmetric Ricci flows and $$F(R,T,Q,T_{m})$$ F ( R , T , Q , T m ) gravity

open access: yesEuropean Physical Journal C: Particles and Fields
We extend the anholonomic frame and connection deformation method, AFCDM, for constructing exact and parametric solutions in general relativity, GR, to geometric flow models and modified gravity theories, MGTs, with nontrivial torsion and nonmetricity ...
Laurenţiu Bubuianu   +3 more
doaj   +1 more source

Singularities of Connection Ricci Flow and Ricci Harmonic Flow

open access: yes, 2013
In this paper, we study the singularities of two extended Ricci flow systems --- connection Ricci flow and Ricci harmonic flow using newly-defined curvature quantities. Specifically, we give the definition of three types of singularities and their corresponding singularity models, and then prove the convergence. In addition, for Ricci harmonic flow, we
openaire   +2 more sources

The anholonomic frame and connection deformation method for constructing off-diagonal solutions in (modified) Einstein gravity and nonassociative geometric flows and Finsler–Lagrange–Hamilton theories

open access: yesEuropean Physical Journal C: Particles and Fields
This article is a status report on the anholonomic frame and connection deformation method, AFCDM, for constructing generic off-diagonal exact and parametric solutions in general relativity, GR, relativistic geometric flows and modified gravity theories,
Laurenţiu Bubuianu   +5 more
doaj   +1 more source

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