Results 31 to 40 of about 558,329 (279)
Doctoral Education in Planning and Urban Studies in Italy: what is it really for? Introduction and Editorial note [PDF]
, 2015 Data show the reduction of academic positions in Italy and invite to reconsider the role of PhD education and training as the highest level of university education.
Falco, Enzo, Rinaldi, Alessandro
core +1 more source
Kinetics of Circulating Plasma Cell-Free DNA in Paediatric Classical Hodgkin Lymphoma [PDF]
, 2016 Levels of plasma cell-free DNA (cfDNA) of a large series of children with classical Hodgkin lymphoma (cHL) were evaluated and analyzed at diagnosis and during chemotherapy treatment in relation with clinical characteristics.
Basso, Giuseppe +11 more
core +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Rivista Italiana di Informatica e Diritto, 2023 La ricerca è essenziale per il progresso scientifico, culturale e sociale e sarà fondamentale per la ripresa economica e sociale nel mondo post-pandemico.
Christophe Geiger, Bernd Justin Jütte
doaj +1 more source
Ricerca preliminare sui fabbisogni formativi per la definizione della figura professionale del Manager dello sviluppo locale [PDF]
, 2002 Indice della ricerca: Introduzione. L'esperienza del Master in International Development: l'azione locale nella prospettiva internazionale. L'evoluzione dell'esperienza. Il Master Operatori allo Sviluppo Gli obiettivi della ricerca.
Frascani, Paolo +4 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effectiveness is the gold standard of clinical research [PDF]
, 2017 Psychological treatments have been shown to be at least as effective (and sometime even more effective) than psychotropic medications for many psychiatric disorders, in particular anxiety disorders, depressive disorders, and personality disorders ...
Formica, Ivan +4 more
core +3 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Soil quality evaluation under agro-silvo-pastoral Mediterranean management systems [PDF]
, 2012 According to Franzluebber (2002) the degree of stratification of soil organic C and N, as well as other parameters, with soil depth, expressed as a ratio, can indicate soil quality or soil ecosystem functioning and sustainability under different ...
Doro, Luca +3 more
core
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source