Results 151 to 160 of about 358,830 (316)

Richness dependence of the recent evolution of clusters of galaxies [PDF]

open access: yes, 2009
We revisit the issue of the recent dynamical evolution of clusters of galaxies using a simple of Abell, Corwin & Olowin (ACO) clusters with z < 0.14, which has been selected such that it does not contain clusters with multiple velocity components nor ...
Tovmassian Hrant, Manolis Plionis
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Species richness, abundance and phenology of fungal fruit bodies over 21 years in a Swiss forest plot

open access: yes, 2001
Fungal fruit bodies were surveyed on a plot area of 1500 m2 from 1975¿99 (excluding 1980¿83) in the fungal reserve La Chaneaz in western Switzerland. Fruit bodies were identified and counted on a weekly basis.
Ayer, F.   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Biodiversity patterns of wetland macroinvertebrate assemblages in the South-Western Cape, South Africa

open access: yes, 2009
Includes bibliographical references (p. 98-108).Despite the recent surge in interest in wetland invertebrates, given their immediate importance in overall wetland functioning, these studies have largely been conducted in the northern hemisphere and very ...
Mlambo, Musa
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Parasite richness.

open access: yes, 2019
Parasite richness for the four forests (MA: Magombera, US: Uzungwa Scarp Nature Reserve; MT: Matundu, MW: Mwanihana). The area of the dots corresponds to the number of samples with the respective parasite richness in each forest, and the bars indicate ...
Francesco Rovero (388826)   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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