Results 171 to 180 of about 57,538 (217)
Some of the next articles are maybe not open access.
Lancet, The, 2003
Rickets, once thought vanquished, is reappearing. In some less developed countries it hardly went away. This seminar reviews the effects of genes, stage of development, and environment on clinical expression of the disease. Rickets can be secondary to disorders of the gut, pancreas, liver, kidney, or metabolism; however, it is mostly due to nutrient ...
Brian, Wharton, Nick, Bishop
exaly +6 more sources
Rickets, once thought vanquished, is reappearing. In some less developed countries it hardly went away. This seminar reviews the effects of genes, stage of development, and environment on clinical expression of the disease. Rickets can be secondary to disorders of the gut, pancreas, liver, kidney, or metabolism; however, it is mostly due to nutrient ...
Brian, Wharton, Nick, Bishop
exaly +6 more sources
Lancet, The, 2014
Rickets, historically referred to as "the English disease", is common worldwide. Absence of phosphate at the growth plate and mineralising bone surfaces due to inadequate vitamin D supply either from sunlight exposure or diet is the main cause. Inherited disorders causing hypophosphataemia have shown the intricacies of phosphate metabolism.
Nicholas J Bishop
exaly +3 more sources
Rickets, historically referred to as "the English disease", is common worldwide. Absence of phosphate at the growth plate and mineralising bone surfaces due to inadequate vitamin D supply either from sunlight exposure or diet is the main cause. Inherited disorders causing hypophosphataemia have shown the intricacies of phosphate metabolism.
Nicholas J Bishop
exaly +3 more sources
Nature Reviews Disease Primers, 2017
Rickets is a bone disease associated with abnormal serum calcium and phosphate levels. The clinical presentation is heterogeneous and depends on the age of onset and pathogenesis but includes bowing deformities of the legs, short stature and widening of joints. The disorder can be caused by nutritional deficiencies or genetic defects.
Thomas O Carpenter +2 more
exaly +3 more sources
Rickets is a bone disease associated with abnormal serum calcium and phosphate levels. The clinical presentation is heterogeneous and depends on the age of onset and pathogenesis but includes bowing deformities of the legs, short stature and widening of joints. The disorder can be caused by nutritional deficiencies or genetic defects.
Thomas O Carpenter +2 more
exaly +3 more sources
Pediatric Emergency Care, 2011
Rickets is disorder of a growing child arising from disorders that result in impaired apoptosis of hypertrophic cells and mineralization of the growth plate. Rickets due to nutritional causes remains an important global problem. The factors responsible for resurgence of rickets among dark-skinned infants living in developed countries include the ...
Mary G, Mallon, Avrum N, Pollock
openaire +4 more sources
Rickets is disorder of a growing child arising from disorders that result in impaired apoptosis of hypertrophic cells and mineralization of the growth plate. Rickets due to nutritional causes remains an important global problem. The factors responsible for resurgence of rickets among dark-skinned infants living in developed countries include the ...
Mary G, Mallon, Avrum N, Pollock
openaire +4 more sources
Hormone Research in Paediatrics, 2000
X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D<sub>3</sub> or 1α-hydroxyvitamin D<sub>3</sub> plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected
SAGGESE, GIUSEPPE, BARONCELLI GI
openaire +3 more sources
X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D<sub>3</sub> or 1α-hydroxyvitamin D<sub>3</sub> plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected
SAGGESE, GIUSEPPE, BARONCELLI GI
openaire +3 more sources
Pediatric Clinics of North America, 2019
Hypophosphatemic rickets, mostly of the X-linked dominant form caused by pathogenic variants of the PHEX gene, poses therapeutic challenges with consequences for growth and bone development and portends a high risk of fractions and poor bone healing, dental problems and nephrolithiasis/nephrocalcinosis.
Martin, Bitzan, Paul R, Goodyer
openaire +2 more sources
Hypophosphatemic rickets, mostly of the X-linked dominant form caused by pathogenic variants of the PHEX gene, poses therapeutic challenges with consequences for growth and bone development and portends a high risk of fractions and poor bone healing, dental problems and nephrolithiasis/nephrocalcinosis.
Martin, Bitzan, Paul R, Goodyer
openaire +2 more sources
Orthopaedic Nursing, 2004
Nutritional (vitamin D deficiency) rickets is now a rarity in the industrial world because of food fortification. Most cases result from hereditary inborn errors of vitamin D metabolism or end-organ unresponsiveness as is exemplified in this case of hypophosphatemic rickets.
openaire +2 more sources
Nutritional (vitamin D deficiency) rickets is now a rarity in the industrial world because of food fortification. Most cases result from hereditary inborn errors of vitamin D metabolism or end-organ unresponsiveness as is exemplified in this case of hypophosphatemic rickets.
openaire +2 more sources
Journal of Pediatric Orthopaedics, 1982
Rickets secondary to hepatobiliary disease is a rare condition; however, the skeletal manifestations are similar to simple nutritional rickets. These skeletal changes include epiphyseal plate abnormalities, pseudofractures, bowing of long bones, scoliosis, and fractures.
M E, Holda, J R, Ryan
openaire +2 more sources
Rickets secondary to hepatobiliary disease is a rare condition; however, the skeletal manifestations are similar to simple nutritional rickets. These skeletal changes include epiphyseal plate abnormalities, pseudofractures, bowing of long bones, scoliosis, and fractures.
M E, Holda, J R, Ryan
openaire +2 more sources
Journal of Pediatric Orthopaedics, 1986
Over a 2-year period, the Orthopaedic Service at the Cincinnati (OH) Children's Hospital Medical Center noted eight patients to present with unusual fractures and musculoskeletal problems due to nutritional rickets. All were black, had been breast-fed until 6-12 months of age, and were vegetarians.
S T, Jacobsen, C K, Hull, A H, Crawford
openaire +2 more sources
Over a 2-year period, the Orthopaedic Service at the Cincinnati (OH) Children's Hospital Medical Center noted eight patients to present with unusual fractures and musculoskeletal problems due to nutritional rickets. All were black, had been breast-fed until 6-12 months of age, and were vegetarians.
S T, Jacobsen, C K, Hull, A H, Crawford
openaire +2 more sources
X-linked hypophosphatemic rickets without ?rickets?
Skeletal Radiology, 1991Wrist and knee radiographs from children with X-linked hypophosphatemic rickets were analyzed and compared with those from normal children and children with established rickets to assess whether radiographically apparent rickets is a consistent abnormality in X-linked hypophosphatemia. The absence or presence of rickets was correctly identified in 94.8%
M J, Econs +8 more
openaire +2 more sources