Transition of Serum Cytokine Concentration in Rickettsia japonica Infection [PDF]
(1) Background. Rickettsia japonica (R. japonica) infection induces severe inflammation, and the disappearance of eosinophil in the acute stage is one of the phenomena. (2) Materials and Methods. In the current study, we measured the serum concentrations
Makoto Kondo +5 more
doaj +2 more sources
Sporadic Human Infections With <i>Rickettsia japonica</i> in Yichang, China, 2021-2023. [PDF]
Japanese spotted fever (JSF) is an easily neglected infectious disease, where misdiagnosis and delayed treatment significantly contribute to poor prognoses in affected patients. Our prospective observational study (2021–2023) systematically characterized 56 JSF cases in Yichang through tripartite analysis encompassing epidemiological distributions ...
Ren Y +10 more
europepmc +2 more sources
Investigation of Anti‐IgG Antibody Responses to the 17‐kDa Outer Membrane Protein of Rickettsia japonica in Individuals From a High‐Risk Area for Japanese Spotted Fever [PDF]
ABSTRACT This study evaluated the seroprevalence and persistence of IgG antibodies against Rickettsia japonica's outer membrane protein (Omp) using a recombinant 17‐kDa antigen and Western blot analysis in residents of Minamiise, Japan—a high‐incidence Japanese spotted fever (JSF) area—and in individuals from non‐endemic regions.
Kondo M, Habe K, Yamanaka K.
europepmc +2 more sources
Systemic lupus erythematosus mimicking Japanese spotted fever due to Rickettsia japonica detection in an eschar: a case report [PDF]
Background Neuropsychiatric systemic lupus erythematosus (NPSLE) is a subset of systemic lupus erythematosus (SLE) characterized by neurological and psychiatric manifestations.
Kento Izuta +8 more
doaj +2 more sources
Diagnostic Assay for Rickettsia japonica [PDF]
We developed a specific and rapid detection system for Rickettsia japonica and R. heilongjiangensis, the causative agents of spotted fever, using a TaqMan minor groove binder probe for a particular open reading frame (ORF) identified by the R.
Nozomu Hanaoka +13 more
doaj +2 more sources
Projecting the potential distribution of Rickettsia japonica in China and Asian adjacent regions under climate change using the Maxent model [PDF]
ObjectiveTo determine the current and future suitable areas of Rickettsia japonica, and to provide a reference for preventing its outbreak and spread.MethodsBased on the geographic distribution of R.
Xiaoxu Wang +11 more
doaj +2 more sources
A case of acute renal dysfunction and multiorgan dysfunction caused by Rickettsia japonica infection [PDF]
This article reports a case of acute renal dysfunction and multi-organ dysfunction syndrome caused by Rickettsia japonica infection. The patient, a 79-year-old male, presented with unexplained fever, fatigue, anorexia, vomiting, and chest tightness ...
Qingyong Zhang, Zhongqiu Teng, Ping Gong
doaj +2 more sources
Geographic shift of Japanese spotted fever and diagnostic overshadowing by COVID-19 testing: A genetically confirmed northernmost case [PDF]
Japanese spotted fever (JSF), caused by Rickettsia japonica, typically presents with fever, rash, and eschar. While endemic to western and southern Japan, recent cases have emerged in urban, non-endemic areas.
Hiroaki Hara +9 more
doaj +2 more sources
Diagnosing and reintegrating traceability of infectious diseases via metagenomic next-generation sequencing: Study of a severe case of Rickettsia japonica infection [PDF]
Background: In this study, we present a case of Japanese spotted fever (JSF) caused by Rickettsia japonica and use this case to investigate the process of diagnosing and reintegrating traceability of infectious diseases via metagenomic next-generation ...
Zhenhua Lu +6 more
doaj +2 more sources
Mitochondrial Dysfunction in <i>Ehrlichia canis</i> Infection. [PDF]
Transmitted by tick vectors, Ehrlichia canis (E. canis) is a Gram‐negative, obligate intracellular bacterium of zoonotic concern that infects both canine and human hosts. Its pathogenesis centers on the targeting of mononuclear phagocytes, where it establishes an intracellular niche by suppressing phagolysosomal fusion and evading immune detection ...
Tong X +13 more
europepmc +2 more sources

