Results 51 to 60 of about 21,637 (264)

Autophagy facilitates intracellular survival of pathogenic rickettsiae in macrophages via evasion of autophagosomal maturation and reduction of microbicidal pro-inflammatory IL-1 cytokine responses

Microbiology Spectrum, 2023
The genus Rickettsia is comprised of obligate intracellular bacterial parasites of a wide range of arthropod and vertebrate hosts. Some Rickettsia species (spp.) are responsible for serious human diseases globally.
Oliver H. Voss, Hodalis Gaytan, Saif Ullah, Mohammad Sadik, Imran Moin, M. Sayeedur Rahman, Abdu F. Azad   +6 more
doaj   +1 more source

Acquisition of Rickettsia rickettsii (Rickettsiales: Rickettsiaceae) by Haemaphysalis longicornis (Acari: Ixodidae) through co-feeding with infected Dermacentor variabilis (Acari: Ixodidae) in the laboratory

Journal of medical entomology, 2023
Haemaphysalis longicornis (Neumann) is an invasive ixodid tick originating from eastern Asia which recently has become established in the United States.
Britny Johnson, Alyssa N. Snellgrove, Sara E. McBride, K. Hartzer, M. Levin, W. Nicholson   +5 more
semanticscholar   +1 more source

Absorption of Rickettsia rickettsii antibodies by Rickettsia rickettsii antigens in four diagnostic tests [PDF]

Journal of Clinical Microbiology, 1983
Immunoabsorption profiles were determined for Rickettsia rickettsii antigens used in four confirmatory tests for detection of antibodies to Rocky Mountain spotted fever. A human serum reactive in the four tests was absorbed with each test antigen and then reexamined by all four tests.
Hassan A. Gaafar, Karim E. Hechemy, N L Carlo, R L Anacker, John A. Fox   +4 more
openaire   +3 more sources

Significant Growth by Rickettsia Species within Human Macrophage-Like Cells Is a Phenotype Correlated with the Ability to Cause Disease in Mammals

Pathogens, 2021
Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent of ...
M. Nathan Kristof, Paige E. Allen, Lane D. Yutzy, Brandon Thibodaux, Christopher D. Paddock, Juan J. Martinez   +5 more
doaj   +1 more source

Laboratory Maintenance of Rickettsia rickettsii [PDF]

Current Protocols in Microbiology, 2008
AbstractThis unit includes protocols for the laboratory maintenance of the obligate intracellular bacterium Rickettsia rickettsii, including propagation in mammalian cell cultures, as well as isolation, counting, and storage procedures. Regulations for working with R. rickettsii in biosafety level 3 containment are also discussed. Curr.
Abdu F. Azad, Nicole C. Ammerman, Magda Beier-Sexton   +2 more
openaire   +3 more sources

Detection of fibrils associated with Rickettsia rickettsii [PDF]

Infection and Immunity, 1983
The ultrastructural appearance of the "halozone" formed at the interface between the spotted fever agent Rickettsia rickettsii and the cytoplasm of persistently infected cultured vole cells (Microtus pennsylvanicus) was studied by transmission electron microscopy. In sections of epoxy-embedded specimens stained with uranyl acetate and lead citrate, the
W Burgdorfer, G P Wray, W J Todd
openaire   +3 more sources

Genomic Comparison of Virulent Rickettsia rickettsii Sheila Smith and Avirulent Rickettsia rickettsii Iowa [PDF]

Infection and Immunity, 2008
ABSTRACT Rickettsia rickettsii is an obligate intracellular pathogen that is the causative agent of Rocky Mountain spotted fever. To identify genes involved in the virulence of R. rickettsii , the genome of an avirulent strain, R.
Daniel E. Sturdevant, Ted Hackstadt, Damon W. Ellison, Stephen F. Porcella, Tina R. Clark, Kimmo Virtaneva   +5 more
openaire   +2 more sources

The Ability of the Invasive Asian Longhorned Tick Haemaphysalis longicornis (Acari: Ixodidae) to Acquire and Transmit Rickettsia rickettsii (Rickettsiales: Rickettsiaceae), the Agent of Rocky Mountain Spotted Fever, Under Laboratory Conditions

Journal of medical entomology, 2020
The invasive Asian longhorned tick, Haemaphysalis longicornis Neumann, was first detected in the United States in 2017. It has since been found in 12 states, and there is concern that the tick's parthenogenetic ability and wide variety of host species ...
Hannah M Stanley, Shelby L. Ford, Alyssa N. Snellgrove, K. Hartzer, Emily B. Smith, Inna Krapiunaya, M. Levin   +6 more
semanticscholar   +1 more source

In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin and pristinamycin [PDF]

Antimicrobial Agents and Chemotherapy, 1989
In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin, pristinamycin, and the pristinamycin compounds, P1 and P2, were determined by a dye uptake assay and a plaque assay. The MICs were 1 microgram/ml for roxithromycin, 2 micrograms/ml for pristinamycin, greater than 256 micrograms/ml for P1, and 2 micrograms/ml for
M Drancourt, D Raoult
openaire   +3 more sources

Long term neurologic sequelae in a Mexican rocky mountain spotted fever case

Brazilian Journal of Infectious Diseases, 2019
During the second half of the twentieth century, neurologic sequelae associated with central nervous system impairment caused by Rickettsia rickettsii were studied widely and exclusively in the United States.
Karla Rossanet Dzul-Rosado, Cesar Lugo-Caballero, Alejandra Salcedo-Parra, Raymundo Daniel López-Soto, Álvaro A. Faccini-Martínez   +4 more
doaj   +1 more source