Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence. [PDF]
, 2019 Rickettsia are obligate intracellular bacteria that evade antimicrobial autophagy in the host cell cytosol by unknown mechanisms. Other cytosolic pathogens block different steps of autophagy targeting, including the initial step of polyubiquitin-coat ...
Burke, Thomas P +9 more
core
Endothelial Cell Proteomic Response to Rickettsia conorii Infection Reveals Activation of the Janus Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT)-Inferferon Stimulated Gene (ISG)15 Pathway and Reprogramming Plasma Membrane Integrin/Cadherin Signaling [PDF]
, 2015 Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762516/Rickettsia conorii is the etiologic agent of Mediterranean spotted fever, a re-emerging infectious disease with significant mortality.
Bechah +43 more
core +1 more source
Experimental Dermatology, Volume 34, Issue 7, July 2025.ABSTRACT This study evaluated the seroprevalence and persistence of IgG antibodies against Rickettsia japonica's outer membrane protein (Omp) using a recombinant 17‐kDa antigen and Western blot analysis in residents of Minamiise, Japan—a high‐incidence Japanese spotted fever (JSF) area—and in individuals from non‐endemic regions.
Makoto Kondo +2 more
wiley +1 more source
Reactivity of monoclonal antibodies to Rickettsia rickettsii with spotted fever and typhus group rickettsiae [PDF]
Journal of Clinical Microbiology, 1987 Analysis of 15 spotted fever group (SFG) and 2 typhus group strains of rickettsiae with a panel of monoclonal antibodies revealed a number of shared and unique epitopes of the 120- and 155-kilodalton surface proteins. All of the SFG strains but neither of the typhus group strains reacted with antibody to the lipopolysaccharidelike antigen of Rickettsia
C Gonzales, R L Anacker, R E Mann
openaire +3 more sources
Ecology, biology and distribution of spotted-fever tick vectors in Brazil
Frontiers in Cellular and Infection Microbiology, 2013 Spotted-fever caused Rickettsia rickettsii infection is in Brazil the major tick-borne zoonotic disease. Recently a second and milder human rickettsiosis caused by an agent genetically related to R.
Matias Pablo Juan Szabó +2 more
doaj +1 more source
Geospatial Analysis of Rickettsial Species [PDF]
, 2019 Rickettsia species are obligate intracellular, arthropod-borne bacteria with a potential to cause multiple diseases including Rocky Mountain spotted fever (RMSF).
Frank, Amy
core +3 more sources
Immunological Reviews, Volume 332, Issue 1, July 2025.ABSTRACT The primary features of the alpha‐gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha‐1,3‐galactose. (ii) In the USA, this IgE ab is induced by bites of the tick Amblyomma americanum. (iii) The anaphylactic reactions to food derived from non‐primate mammals
Thomas A. E. Platts‐Mills +3 more
wiley +1 more source
Clinical manifestations of Rickettsia rickettsii in a familial outbreak in Panama
Travel Medicine and Infectious Disease, 2023 We report an isolated outbreak of Rickettsia rickettsii in the Ngäbe-Buglé indigenous region, located 750 m (tropical wet) above sea level, in a jungle and mountainous area of Western Panama. Seven members of a family were infected simultaneously, resulting in four deaths.
Carlos A. Daza T +11 more
openaire +2 more sources
Legionella pneumophila modulates the host cytoskeleton by an effector of transglutaminase activity
mLife, Volume 4, Issue 3, Page 232-248, June 2025.Abstract The bacterial pathogen Legionella pneumophila delivers more than 330 effector proteins into host cells through its Dot/Icm type IV secretion system (T4SS) to facilitate its intracellular replication. A number of these effectors modulate organelle trafficking pathways to create a membrane‐bound niche called the Legionella‐containing vacuole ...
Yan Liu, Yao Liu, Zhao‐Qing Luo
wiley +1 more source
In vitro susceptibilities of Coxiella burnetii, Rickettsia rickettsii, and Rickettsia conorii to the fluoroquinolone sparfloxacin [PDF]
Antimicrobial Agents and Chemotherapy, 1991 In vitro susceptibilities of Rickettsia rickettsii, Rickettsia conorii, and Coxiella burnetii to the new fluoroquinolone sparfloxacin (AT-4140; RP 64206) were determined. Plaque and dye uptake assays were used to measure the MICs against R. rickettsii and R. conorii. The susceptibilities of C.
P. Bres +3 more
openaire +3 more sources