Results 121 to 130 of about 72,471 (294)
Antimycobacterial Activity of Rifampin Under In Vitro and Simulated In Vivo Conditions [PDF]
K. D. Stottmeier +2 more
openalex +1 more source
De Novo Design and Synthesis of Novel Benzoxazinone Derivatives Targeting Dihydroxyacid Dehydratase
ABSTRACT Dihydroxyacid dehydratase (DHAD), a key enzyme in the branched‐chain amino acid (BCAA) synthesis pathway, is a promising herbicide target. Currently, no commercial herbicides target DHAD, and no inhibitors are in development. Structural analysis suggests that coordination with iron–sulfur clusters and hydrophobic interactions with Tyr215 and ...
Bo He +7 more
wiley +1 more source
Replication of mycoplasmavirus MVL51. IV. Inhibition of viral synthesis by rifampin [PDF]
Jyotirmoy Das, Jack Maniloff
openalex +1 more source
Implant-based drug delivery necessitates a rigorous quantitative assessment and quality control of the drug release behavior. In this context, a fast simultaneous UV-VIS spectrometer quantification method was developed for an antibiotic dual drug system.
Eickner Thomas +5 more
doaj +1 more source
Antimicrobial Susceptibility Testing of Pneumococci: Determination of Kirby-Bauer Breakpoints for Penicillin G, Erythromycin, Clindamycin, Tetracycline, Chloramphenicol, and Rifampin [PDF]
Michael R. Jacobs +4 more
openalex +1 more source
Abstract Fruquintinib is a highly selective oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, approved by the US Food and Drug Administration and the European Commission for the treatment of previously treated metastatic colorectal cancer (mCRC), regardless of biomarker status. This study used concentration QT interval (C‐QTc)
Xiaofei Zhou +7 more
wiley +1 more source
Rifampin resistance mutation of Bacillus subtilis altering the electrophoretic mobility of the beta subunit of ribonucleic acid polymerase [PDF]
Thomas Linn +2 more
openalex +1 more source
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora +4 more
wiley +1 more source
ABSTRACT Aim To assess the prevalence of post‐operative infection related to surgical third molar extractions at a university teaching hospital. The secondary outcome was to investigate risk factors relating to post‐operative infections, including the use of prophylactic antibiotics.
Joshal Mehta, Riddhika Ram, Peter Reher
wiley +1 more source
Mutations in 1700 Bp Fragment of Rpob Gene of Multi-drug Resistant Mycobacterium Tuberculosis Isolate [PDF]
This research aimed to amplify a 1700 bp fragment of rpoB gene of multidrug resistance M. tuberculosis (MDR-TB) isolate and determine types of mutation beyond the core region (hot-spot region).
Junitha, I. K. (I) +3 more
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