Results 121 to 130 of about 86,105 (313)

The Study of the Protective Effect of Black Cumin (Nigella sativa linn.)Ethanolic Extract Against Rifampin-induced Hepatotoxicity in Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives:Anti-tuberculosis drug, rifampin, is toxic for liver. This study was conducted to determine the preventive effects of black cumin (Nigella sativaLinn.) extract against rifampin-induced hepatotoxicity in rats. Methods: In this
Mehrdad Neshat Gharamaleki, Daryoush Mohajeri   +1 more
doaj  

New combination for patients with latent tuberculosis infection: A pilot study

Journal of Medical Sciences, 2018
Background: Latent tuberculosis infection (LTBI) is characterized by the presence of immune responses to Mycobacterium tuberculosis without clinical evidence of active TB.
Te-Yu Lin, Feng-Cheng Liu
doaj   +1 more source

Oral-Only Linezolid-Rifampin Is Highly Effective Compared with Other Antibiotics for Periprosthetic Joint Infection

Journal of Bone and Joint Surgery. American volume, 2017
Background: The medical treatment of periprosthetic joint infection (PJI) involves prolonged systemic antibiotic courses, often with suboptimal clinical outcomes including increased morbidity and health-care costs.
John M. Thompson, V. Saini, Alyssa G. Ashbaugh, Robert J. Miller, A. Ordonez, R. Ortines, Yu Wang, R. Sterling, Sanjay K. Jain, L. Miller   +9 more
semanticscholar   +1 more source

Discospondylitis as a consequence of jugular vein septic thrombophlebitis in a Standardbred gelding

Equine Veterinary Education, Volume 37, Issue 8, Page e159-e165, August 2025.
Summary This report describes the identification of C7‐T1 discospondylitis on myelography and confirmed on postmortem computed tomography and necropsy in a 4‐year‐old Standardbred gelding as the consequence of jugular vein catheterisation and secondary septic thrombophlebitis. Staphylococcus aureus was isolated from both sites.
F. Payette, J. A. Demchur, K. W. Bills, D. G. Levine, A. L. Johnson   +4 more
wiley   +1 more source

Decreased Time to Treatment Initiation for Multidrug-Resistant Tuberculosis Patients after Use of Xpert MTB/RIF Test, Latvia

Emerging Infectious Diseases, 2016
Few studies have examined whether the Xpert MTB/RIF test improves time to treatment initiation for persons with multidrug-resistant tuberculosis (MDR TB). We determined the impact of this test in Latvia, where it was introduced in 2010. After descriptive
Helen R. Stagg, Peter A. White, Vija Riekstiņa, Andra Cīrule, Ģirts Šķenders, Vaira Leimane, Liga Kuksa, Gunta Dravniece, James Brown, Charlotte Jackson   +9 more
doaj   +1 more source

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial [PDF]

, 2017
Background : By the early 1980s, tuberculosis treatment was shortened from 24 to 6 months, maintaining relapse rates of 1-2%. Subsequent trials attempting shorter durations have failed, with 4-month arms consistently having relapse rates of 15-20%.
Alland, D, Arora, K, Barry Iii, CE, Cai, Y, Chen, RY, Dawson, R, Diacon, AH, Dodd, LE, Duan, H, Duvenhage, M, Gao, Q, Goldfeder, LC, Hatherill, M, Jiang, Q, Jin, X, Liang, L, Liu, X, Loxton, AG, Ma, Z, Malherbe, ST, Pan, S, Predict TB Study Group, Rosenthal, A, Smith, B, Song, T, Tameris, M, Tartakovsky, M, Thienemann, F, Via, LE, Walzl, G, Whalen, C, Wilkinson, RJ, Winter, J, Xing, J, Zhang, G, Zhu, H   +35 more
core   +2 more sources

Treatment completion for latent tuberculosis infection: a retrospective cohort study comparing 9 months of isoniazid, 4 months of rifampin and 3 months of isoniazid and rifapentine

BMC Infectious Diseases, 2017
BackgroundThe U.S. Centers for Disease Control and Prevention (CDC) recommended a new regimen for treatment of latent tuberculosis (three months of weekly isoniazid and rifapentine) in late 2011. While completion rates of this regimen were reported to be
A. McClintock, M. Eastment, C. McKinney, Caroline Pitney, M. Narita, David R. Park, S. Dhanireddy, A. Molnar   +7 more
semanticscholar   +1 more source

Electrochemical Catheter Hub Operated by a Wearable Micropotentiostat Prevents Acinetobacter baumannii Infection In Vitro

Biotechnology and Bioengineering, Volume 122, Issue 7, Page 1828-1839, July 2025.
ABSTRACT Intraluminal infection of central venous catheters, used for long‐term treatment, can result in central line‐associated bloodstream infection (CLABSI). These infections can be challenging to prevent and treat due to formation of biofilms within catheter lumens, which shield bacteria from the human immune response and conventional antimicrobial
Majid Al‐Qurahi, Derek Fleming, Won‐Jun Kim, Ibrahim Bozyel, Robin Patel, Haluk Beyenal   +5 more
wiley   +1 more source

Fluorescent Protein Expressing Rickettsia buchneri and Rickettsia peacockii for Tracking Symbiont-Tick Cell Interactions

Veterinary Sciences, 2016
Rickettsiae of indeterminate pathogenicity are widely associated with ticks. The presence of these endosymbionts can confound a One Health approach to combatting tick-borne diseases.
Timothy J. Kurtti, Nicole Y. Burkhardt, Chan C. Heu, Ulrike G. Munderloh   +3 more
doaj   +1 more source

Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements [PDF]

, 2014
Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements.
Ahituv, Nadav, Aldred, Shelley Force, Desta, Zeruesenay, Eckalbar, Walter L., Giacomini, Kathleen M., Hoffmann, Thomas J., Jones, Stacy L., Liu, Yunlong, Luizon, Marcelo R., Morrissey, Kari M., Ramamoorthy, Anuradha, Skaar, Todd C., Smith, Robin P., Sun, Xuefeng, Trinklein, Nathan D.   +14 more
core   +4 more sources