Results 101 to 110 of about 26,072 (305)

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Structure of a functional cap-binding domain in Rift Valley fever virus L protein

PLoS Pathogens, 2019
Rift Valley fever virus (RVFV) belongs to the family of Phenuiviridae within the order of Bunyavirales. The virus may cause fatal disease both in livestock and humans, and therefore, is of great economical and public health relevance.
N. Gogrefe, S. Reindl, S. Günther, M. Rosenthal   +3 more
semanticscholar   +1 more source

Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice. [PDF]

PLoS ONE, 2018
Rift Valley fever (RVF) in humans is usually mild, but, in a subset of cases, can progress to severe hepatic and neurological disease. Rodent models of RVF generally develop acute severe clinical disease.
Jessica R Spengler, Anita K McElroy, Jessica R Harmon, JoAnn D Coleman-McCray, Stephen R Welch, James G Keck, Stuart T Nichol, Christina F Spiropoulou   +7 more
doaj   +1 more source

Computer-Selected Antiviral Compounds: Assessing In Vitro Efficacies against Rift Valley Fever Virus

Viruses
Rift Valley fever is a zoonotic viral disease transmitted by mosquitoes, impacting both humans and livestock. Currently, there are no approved vaccines or antiviral treatments for humans.
Cigdem Alkan, Terrence O’Brien, Victor Kenyon, Tetsuro Ikegami   +3 more
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B., Dong, C., Dong, H., Elliott, R., Li, P.   +4 more
core   +1 more source

Advances in Animal Disease Surveillance and Information Systems and Their Role in Disease Control and Prevention: Implications in Ethiopia

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
• The current advances in animal disease surveillance and information systems include mobile applications, geospatial technologies, advanced diagnostics, social media platforms and digital surveillance systems. • The application of advanced technologies to disease surveillance and information systems enhances early disease detection and warning ...
Aweke Engdawork, Haileleul Negussie
wiley   +1 more source

Biologically Informed Individual-Based Network Model for Rift Valley Fever in the US and Evaluation of Mitigation Strategies [PDF]

, 2016
Citation: Scoglio, C. M., Bosca, C., Riad, M. H., Sahneh, F. D., Britch, S. C., Cohnstaedt, L. W., & Linthicum, K. J. (2016). Biologically Informed Individual-Based Network Model for Rift Valley Fever in the US and Evaluation of Mitigation Strategies ...
Bosca, C., Britch, S. C., Cohnstaedt, L. W., Linthicum, K. J., Riad, M. H., Sahneh, Faryad D., Scoglio, Caterina M.   +6 more
core   +3 more sources

Estimation of Rift Valley fever virus spillover to humans during the Mayotte 2018–2019 epidemic

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Rift Valley fever (RVF) is an emerging, zoonotic hemorrhagic fever, affecting mainly livestock and humans in Africa. Despite its growing global concern, the impact of control measures on epidemic dynamics using empirical data has not been ...
R. Métras, W. Edmunds, Chouanibou Youssouffi, L. Dommergues, G. Fournié, A. Camacho, S. Funk, E. Cardinale, Gilles Le Godais, Soihibou Combo, L. Filleul, H. Youssouf, Marion Subiros   +12 more
semanticscholar   +1 more source

Landscapes associated with Japanese encephalitis virus in Australia reflect the functional biogeography of waterbirds

Ecosphere, Volume 16, Issue 10, October 2025.
Abstract Japanese encephalitis virus (JEV), a zoonotic, mosquito‐borne virus, has broad circulation across the Central Indo‐Pacific biogeographical region (CIPBR) and has recently expanded dramatically within this region across southeastern Australia over the summer of 2021–2022.
Michael G. Walsh, Cameron Webb, Victoria Brookes   +2 more
wiley   +1 more source

Potential of Using Capripoxvirus Vectored Vaccines Against Arboviruses in Sheep, Goats, and Cattle

Frontiers in Veterinary Science, 2019
The genus capripoxvirus consists of sheeppox virus, goatpox virus, and lumpy skin disease virus, which affect sheep, goats, and cattle, respectively. Together capripoxviruses cause significant economic losses to the sheep, goat, and cattle industry where
Mahder Teffera, Mahder Teffera, Shawn Babiuk, Shawn Babiuk   +3 more
doaj   +1 more source