Results 51 to 60 of about 1,907,587 (220)

Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in Europe [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus that has caused widespread disease in cattle, sheep and goats in Europe. Like other orthobunyaviruses, SBV is characterized by a tripartite negative-sense RNA genome that encodes four ...
Szemiel, A.M., McLees, A., Li, P., van Knippenberg, I.C., McLees, Angela, Li, Ping, Shi, X., van Knippenberg, Ingeborg C., Elliott, Richard M., Szemiel, Agnieszka M., Shi, Xiaohong, Koudriakova, E., Koudriakova, Elina, Blakqori, G., Elliott, R.M., Blakqori, Gjon   +15 more
core   +1 more source

Advances in Understanding Neuropathogenesis of Rift Valley Fever Virus

Annual Review of Virology, 2022
Rift Valley fever virus (RVFV) is an emerging arboviral pathogen that causes disease in both livestock and humans. Severe disease manifestations of Rift Valley fever (RVF) in humans include hemorrhagic fever, ocular disease, and encephalitis. This review describes the current understanding of the pathogenesis of RVF encephalitis.
Connors, Kaleigh A., Hartman, Amy L.
openaire   +2 more sources

Prevalence and associated factors of human haemorrhagic fevers in Senegal: a comprehensive analysis of Hantaan, Crimean-Congo haemorrhagic fever and Rift Valley fever

Frontiers in Public Health
IntroductionViral haemorrhagic fevers such as Rift Valley fever, Crimean-Congo haemorrhagic fever, and hantavirus disease continue to threaten public health in Africa.
Maryam Diarra, Safietou Sankhe, Mamadou Aliou Barry, Fatoumata Diene Sarr, Mamadou Korka Kindy Diallo, Joseph Faye, Mame Astou Gassama, Maimouna Mbanne, Ousmane Faye, Cheikh Talla, Robab Katani, Keersten Ricks, Moussa Moise Diagne, Jessica Radzio-Basu, Cheikh Loucoubar   +14 more
doaj   +1 more source

A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

Cell Reports, 2018
Summary: The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response.
Elizabeth R. Allen, Stefanie A. Krumm, Jayna Raghwani, Steinar Halldorsson, Angela Elliott, Victoria A. Graham, Elina Koudriakova, Karl Harlos, Daniel Wright, George M. Warimwe, Benjamin Brennan, Juha T. Huiskonen, Stuart D. Dowall, Richard M. Elliott, Oliver G. Pybus, Dennis R. Burton, Roger Hewson, Katie J. Doores, Thomas A. Bowden   +18 more
doaj   +1 more source

Reanalysis of the 2000 Rift Valley fever outbreak in Southwestern Arabia.

PLoS ONE, 2020
The first documented Rift Valley hemorrhagic fever outbreak in the Arabian Peninsula occurred in northwestern Yemen and southwestern Saudi Arabia from August 2000 to September 2001.
Compton J Tucker, Katherine A Melocik, Assaf Anyamba, Kenneth J Linthicum, Shamsudeen F Fagbo, Jennifer L Small   +5 more
doaj   +1 more source

Right to Food in Sub‐Saharan Africa: Challenges, Policies, and Sustainable Strategies

Sustainable Development, EarlyView.
ABSTRACT This article examines the multifaceted issue of food security in Sub‐Saharan Africa and the critical importance of upholding rights to food in the region. It explores the challenges posed by food insecurity, analyzes existing policies and interventions, and proposes sustainable strategies to enhance food security.
Helen Onyeaka, Adenike A. Akinsemolu, Phemelo Tamasiga, Ogueri Nwaiwu, Elijah Kolawole Oladipo, Kehinde Abolade Aderibigbe, Taghi Miri   +6 more
wiley   +1 more source

Spread and Control of Rift Valley Fever virus after accidental introduction in the Netherlands: a modelling study. [PDF]

, 2011
Rift Valley Fever (RVF) is a zoonotic vector-borne infection and causes a potentially severe disease in both humans and young animals. The Ministry of Economic Affairs, Agriculture and Innovation (EL&I) is interested in the risk of an outbreak of Rift ...
Fischer, E.A.J., Boender, G.J., van Roermund, H.J.W., Koeijer, A.A., de, Nodelijk, G., Roermund, H.J.W., van, de Koeijer, A.A.   +6 more
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Identification and evaluation of antivirals for Rift Valley fever virus [PDF]

Veterinary Microbiology, 2019
Rift Valley fever virus (RVFV) is the causative agent of Rift Valley fever (RVF) that affects both livestock and humans. There are neither fully licensed RVF vaccines available for human or animal use, nor effective antiviral drugs approved for human use in the U.S.
Yuekun Lang, Yonghai Li, Dane Jasperson, Jamie Henningson, Jinhwa Lee, Jingjiao Ma, Yuhao Li, Michael Duff, Haixia Liu, Dingping Bai, Scott McVey, Juergen A. Richt, Tetsuro Ikegami, William C. Wilson, Wenjun Ma   +14 more
openaire   +2 more sources

Rift Valley Fever Virus

Rift Valley fever virus (RVFV) is a negative-sense, single-stranded RNA virus in the genus Phlebovirus of the family Phenuviridae. It is an arbovirus transmitted mainly by mosquitoes. RVFV is an emerging zoonotic disease where humans can get infected via exposure of mucosa or broken skin to infected animals or through mosquito transmission. The disease
Binu T. Velayudhan, Shaun van den Hurk
openaire   +2 more sources

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source