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Zoonotic arbovirus infections in cattle in Mozambique with special reference to Crimean-Congo hemorrhagic fever virus (CCHFV) and Rift Valley fever virus (RVFV) [PDF]

open access: yesVirology Journal
Background Arboviruses pose a great threat to public health in sub-Saharan African countries. Mozambique is located in a region that is prone to climate change-related devastation, including heavy rainfalls and severe droughts that favor the emergence of
José Fafetine   +6 more
doaj   +6 more sources

Comparison of RT-qPCR and RT-ddPCR with Rift valley fever virus (RVFV) RNA [PDF]

open access: yesScientific Reports, 2023
Rift valley fever (RVF) is an important zoonotic disease caused by the Rift valley fever virus (RVFV) which can affect ruminants and humans. In this study, a comparison was done of the reverse transcription-quantitative polymerase chain reaction (RT-qPCR)
Changwoo Park   +4 more
doaj   +4 more sources

Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy. [PDF]

open access: yesCell Biosci, 2021
Abstract Background Although multiple studies have demonstrated a role for exosomes during virus infections, our understanding of the mechanisms by which exosome exchange regulates immune response during viral infections and affects viral pathogenesis is still in its infancy.
Alem F   +14 more
europepmc   +5 more sources

A Multi-Host Approach to Quantitatively Assess the Role of Dogs as Sentinels for Rift Valley Fever Virus (RVFV) Surveillance in Madagascar. [PDF]

open access: yesViruses
Sentinel animals may play a key role in the surveillance of arbovirus circulation, particularly in developing countries. This study aimed to assess the relevance of using dogs as sentinel animals for Rift Valley fever virus (RVFV) surveillance in Madagascar.
Ramaroson HS   +17 more
europepmc   +6 more sources

Cloning and phylogenetic analysis of N protein gene from Rift Valley Fever Virus (RVFV). [PDF]

open access: yesBioinformation
Rift Valley Fever (RVF) is a mosquito-borne viral zoonosis caused by RVFV in humans and livestock. Currently, there are no approved vaccines or antiviral therapies available. Additionally, in Saudi Arabia, there is a lack of a routine screening system to monitor RVFV in humans and animals which hinders to design and develop the preventive measures as ...
Hassan AM   +4 more
europepmc   +3 more sources

Characterization of Two Neutralizing Antibodies against Rift Valley Fever Virus Gn Protein

open access: yesViruses, 2020
The Rift Valley fever virus (RVFV) is an arthropod-borne virus that can not only cause severe disease in domestic animals but also in humans. However, the licensed vaccines or available therapeutics for humans do not exist.
Meng Hao   +13 more
doaj   +3 more sources

Maternal vaccination protects dams and prevents in utero transmission of Rift Valley fever virus in rats [PDF]

open access: yesmBio
In utero transmission and spontaneous fetal death are hallmarks of Rift Valley fever virus (RVFV) infection in pregnant animals. Compounding evidence indicates pregnant individuals are particularly vulnerable to RVFV, as in utero transmission and ...
Austin T. Hertel   +5 more
doaj   +2 more sources

Phylogeography of Rift Valley Fever Virus in Africa and the Arabian Peninsula.

open access: yesPLoS Neglected Tropical Diseases, 2017
Rift Valley Fever is an acute zoonotic viral disease caused by Rift Valley Fever virus (RVFV) that affects ruminants and humans in Sub-Saharan Africa and the Arabian Peninsula.
Abdallah M Samy   +2 more
doaj   +3 more sources

Efficacy of different DNA and MVA prime-boost vaccination regimens against a Rift Valley fever virus (RVFV) challenge in sheep 12 weeks following vaccination. [PDF]

open access: yesVet Res, 2018
The aim of this work was to evaluate the immunogenicity and efficacy of DNA and MVA vaccines encoding the RVFV glycoproteins Gn and Gc in an ovine model of RVFV infection. Adult sheep of both sexes were challenged 12 weeks after the last immunization and clinical, virological, biochemical and immunological consequences, were analyzed.
Lorenzo G   +3 more
europepmc   +8 more sources

Rift Valley Fever Virus Is Lethal in Different Inbred Mouse Strains Independent of Sex

open access: yesFrontiers in Microbiology, 2020
Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting humans and livestock in Africa and the Arabian Peninsula. The majority of human cases are mild and self-limiting; however, severe cases can result in hepatitis, encephalitis, or hemorrhagic
Haley N. Cartwright   +5 more
doaj   +3 more sources

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