Results 11 to 20 of about 1,901,827 (184)

The Pathogenesis of Rift Valley Fever

Viruses, 2011
Rift Valley fever (RVF) is an emerging zoonotic disease distributed in sub-Saharan African countries and the Arabian Peninsula. The disease is caused by the Rift Valley fever virus (RVFV) of the family Bunyaviridae and the genus Phlebovirus. The virus is
Tetsuro Ikegami, Shinji Makino
doaj   +2 more sources

Inhibitory effects of bioactive molecules against nonstructural protein (NSs) of Rift Valley Fever Virus (RVFv): A molecular modeling study

Heliyon
Rift Valley fever (RVF), a vector-borne zoonotic disease caused by the Rift Valley Fever Virus arbovirus (RVFv), has had a significant impact on livestock and poses a risk to human health. This RNA virus belongs to the Bunyaviridae family of the genus Phlebovirus. Limited treatment options are available for this mosquito-borne RVF disease.
David J Kelvin, Rohit Shukla, Mansi Dutt   +2 more
exaly   +3 more sources

Genetically Modified Rabies Virus Vector-Based Rift Valley Fever Virus Vaccine is Safe and Induces Efficacious Immune Responses in Mice

Viruses, 2019
Rift Valley fever virus (RVFV), which causes Rift Valley fever (RVF), is a mosquito-borne zoonotic pathogen that causes serious morbidity and mortality in livestock and humans.
Shengnan Zhang, Meng Hao, Na Feng, Hongli Jin, Feihu Yan, Hang Chi, Hualei Wang, Qiuxue Han, Jianzhong Wang, Gary Wong, Bo Liu, Jun Wu, Yuhai Bi, Tiecheng Wang, Weiyang Sun, Yuwei Gao, Songtao Yang, Yongkun Zhao, Xianzhu Xia   +18 more
doaj   +3 more sources

Interepidemic Rift Valley Fever Virus Seropositivity, Northeastern Kenya

Emerging Infectious Diseases, 2008
Most outbreaks of Rift Valley fever (RVF) occur in remote locations after floods. To determine environmental risk factors and long-term sequelae of human RVF, we examined rates of previous Rift Valley fever virus (RVFV) exposure by age and location ...
A. Desiree LaBeaud, Eric M. Muchiri, Malik Ndzovu, Mariam T. Mwanje, Samuel Muiruri, Clarence J. Peters, Charles H. King   +6 more
doaj   +2 more sources

Survey of Rift Valley Fever Virus Antibodies and Risk Factors in Small Ruminants in Maiduguri, Borno State, Nigeria: A Cross-Sectional Serological Study. [PDF]

Vet Med Sci
High seroprevalence of Rift Valley fever virus antibodies (47.9%) in small ruminants in Maiduguri indicates substantial past exposure. Age, sex, and residence in flood‐prone areas were significant risk factors, highlighting the need for targeted surveillance and vector control to reduce livestock and public health impacts.
Mohammed S, Mohammed A, Saidu AS, Gashua MM, Adamu SG, Yusuf IM, Jigbin D, Tijani AO, Musa HI.   +8 more
europepmc   +2 more sources

Paving the way for human vaccination against Rift Valley fever virus: A systematic literature review of RVFV epidemiology from 1999 to 2021 [PDF]

PLOS Neglected Tropical Diseases, 2021
Background Rift Valley fever virus (RVFV) is a lethal threat to humans and livestock in many parts of Africa, the Arabian Peninsula, and the Indian Ocean. This systematic review’s objective was to consolidate understanding of RVFV epidemiology during 1999–2021 and highlight knowledge gaps relevant to plans for ...
Keli N. Gerken, A. Desirée LaBeaud, Henshaw Mandi, Maïna L’Azou Jackson, J. Gabrielle Breugelmans, Charles H. King   +5 more
openaire   +4 more sources

Natural hosts and animal models for Rift Valley fever phlebovirus

Frontiers in Veterinary Science, 2023
Rift Valley fever phlebovirus (RVFV) is a zoonotic mosquito-transmitted arbovirus, presenting a serious threat to humans and animals. Susceptible hosts are of great significance for the prevention of RVFV.
Yuqing Xu, Yuqing Xu, Yuqing Xu, Xiao Wang, Xiao Wang, Lu Jiang, Lu Jiang, Yixuan Zhou, Yixuan Zhou, Yihan Liu, Yihan Liu, Fei Wang, Fei Wang, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +15 more
doaj   +1 more source

Rift Valley Fever and Crimean-Congo Hemorrhagic Fever Viruses in Ruminants, Jordan

Emerging Infectious Diseases, 2021
The epidemiology of Rift Valley fever virus (RVFV) and Crimean-Congo hemorrhagic fever virus (CCHFV) in Jordan is unknown. Our investigation showed 3% of 989 tested dairy cattle, sheep, and goats were RVFV seropositive and 14% were CCHFV seropositive ...
Mohammad M. Obaidat, James C. Graziano, Maria Morales-Betoulle, Shelley M. Brown, Cheng-Feng Chiang, John D. Klena   +5 more
doaj   +1 more source

Mycoplasma Contamination Alters the Expression Profile of Pro-Inflammatory Cytokines by Human Innate Immune Cells. [PDF]

Cell Biochem Funct
ABSTRACT The impact of Mycoplasma contaminations on in vitro test systems has been extensively discussed and in vitro studies have demonstrated various effects on the physiology of the contaminated cell line. Thus far, little is known about the effect of biologically active substances, such as viruses produced in contaminated cell lines on primary ...
Gogesch P, Kronhart S, Niles MA, Kochs G, Waibler Z, Anzaghe M.   +5 more
europepmc   +2 more sources

A single immunization with MVA expressing GnGc glycoproteins promotes epitope-specific CD8+-T cell activation and protects immune-competent mice against a lethal RVFV infection. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Rift Valley fever virus (RVFV) is a mosquito-borne pathogen causing an important disease in ruminants often transmitted to humans after epizootic outbreaks in African and Arabian countries.
Elena López-Gil, Gema Lorenzo, Esther Hevia, Belén Borrego, Martin Eiden, Martin Groschup, Sarah C Gilbert, Alejandro Brun   +7 more
doaj   +1 more source