Results 31 to 40 of about 1,901,827 (184)

Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase [PDF]

, 2011
The viral RNA-dependent RNA polymerase (RdRp; L protein) of Rift Valley fever virus (RVFV; family Bunyaviridae) is a 238 kDa protein that is crucial for the life cycle of the virus, as it catalyses both transcription of viral mRNAs and replication of the
Brennan, Benjamin, Richard M. Elliott, Li, Ping, Ping Li, Elliott, Richard M., Benjamin Brennan   +5 more
core   +1 more source

Spatial and Temporal Pattern of Rift Valley Fever Outbreaks in Tanzania; 1930 to 2007 [PDF]

, 2014
Rift Valley fever (RVF)-like disease was first reported in Tanzania more than eight decades ago and the last large outbreak of the disease occurred in 2006–07. This study investigates the spatial and temporal pattern of RVF outbreaks in Tanzania over the
Mboera Leonard E. G., Dautu George, Kivaria, F., Pfeiffer Dirk U., Esron D Karimuribo, UN, Food & Agr Org, Karimuribo, E.D., Sindato, Calvin, Pfeiffer, D U, Mboera, Leonard E. G., Leonard E G Mboera, Sokoine University, Tanzania, Nat Health Lab Service, South Africa, Dautu, G., Pfeiffer, Dirk U., Dirk U Pfeiffer, George Dautu, Karimuribo Esron D., Janusz T Paweska, Bett, Bernard K., Paweska, J.T., Bernard, B, Kivaria Fredrick, Kivaria, Fredrick, Paweska, Janusz T., Kivaria, F, Fredrick Kivaria, Karimuribo, E D, Witwatersrand, South Africa, Zambia, Nat Instit For Medical Research, Bernard Bett, Mboera, L E G, Sindato, C., Dautu, G, Sindato, C, Paweska, J T, Bett Bernard, Sindato Calvin, Bernard, Bett, Calvin Sindato, Mboera, L.E.G., ILRI, Karimuribo, Esron D., Paweska Janusz T., Dautu, George   +45 more
core   +1 more source

Aedes mosquito saliva modulates Rift Valley fever virus pathogenicity. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Rift Valley fever (RVF) is a severe mosquito-borne disease affecting humans and domestic ruminants. Mosquito saliva contains compounds that counteract the hemostatic, inflammatory, and immune responses of the host.
Alain Le Coupanec, Divya Babin, Laurence Fiette, Grégory Jouvion, Patrick Ave, Dorothee Misse, Michèle Bouloy, Valerie Choumet   +7 more
doaj   +1 more source

Predicting Distribution of Aedes Aegypti and Culex Pipiens Complex, Potential Vectors of Rift Valley Fever Virus in Relation to Disease Epidemics in East Africa. [PDF]

, 2013
The East African region has experienced several Rift Valley fever (RVF) outbreaks since the 1930s. The objective of this study was to identify distributions of potential disease vectors in relation to disease epidemics.
Kimera, Sharadhuli Iddi, Mweya, Clement Nyamunura, Kija, John Bukombe, Mboera, Leonard E G   +3 more
core   +1 more source

NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

Nature Communications, 2020
Rift Valley fever virus (RVFV) can cause severe diseases in humans, including encephalitis. Here the authors show that NSs, the major virulence factor of RVFV, is an amyloidogenic protein forming fibrils in infected mouse brains and causing increased ...
Psylvia Léger, Eliana Nachman, Karsten Richter, Carole Tamietti, Jana Koch, Robin Burk, Susann Kummer, Qilin Xin, Megan Stanifer, Michèle Bouloy, Steeve Boulant, Hans-Georg Kräusslich, Xavier Montagutelli, Marie Flamand, Carmen Nussbaum-Krammer, Pierre-Yves Lozach   +15 more
doaj   +1 more source

Exploratory Space-Time Analyses of Rift Valley Fever in South Africa in 2008-2011 [PDF]

, 2012
Background: Rift Valley fever (RVF) is a zoonotic arbovirosis for which the primary hosts are domestic livestock (cattle, sheep and goats). RVF was first described in South Africa in 1950-1951.
Thompson Peter N., White Richard G., Porphyre Thibaud, Thompson, P N, Pfeiffer Dirk U., Collins, LM, Nollions, Lisa M., Collins Lisa M., LSHTM, Kemp, A, Kemp, A., Thompson, P.N., White, Richard G, White, Richard G., Pfeiffer, D U, Porphyre, Thibaud, Pretoria, Métras, Raphaëlle, Lisa M Collins, White, R G, Edinburgh, Peter N Thompson, Porphyre, T, Nat Health Lab Service, South Africa, Queen's Belfast, White, R.G., Kemp, Alan, Pfeiffer, Dirk U., Dirk U Pfeiffer, Thompson, P.N. (Peter N.), Métras, R., Thompson, Peter N, Richard G White, Porphyre, T., Metras, R, Collins, L M, Thompson, PN, Kemp Alan, Alan Kemp, White, RG, Pfeiffer, Dirk U, Thibaud Porphyre, Métras Raphaëlle, Pfeiffer, DU, Collins, L.M., Collins, Lisa M, Pfeiffer, D.U., Raphaëlle Métras   +47 more
core   +1 more source

Development of a Visible Reverse Transcription-Loop-Mediated Isothermal Amplification Assay for the Detection of Rift Valley Fever Virus

Frontiers in Microbiology, 2020
Rift Valley fever (RVF) is a severe infectious disease, which can through mosquito bites, direct contact and aerosol transmission infect sheep, goats, people, camels, cattle, buffaloes, and so on. In this paper, a conserved region of the S RNA segment of
Qiuxue Han, Qiuxue Han, Shengnan Zhang, Dongping Liu, Feihu Yan, Feihu Yan, Hualei Wang, Pei Huang, Pei Huang, Jinhao Bi, Jinhao Bi, Hongli Jin, Hongli Jin, Na Feng, Zengguo Cao, Zengguo Cao, Yuwei Gao, Yuwei Gao, Hang Chi, Hang Chi, Songtao Yang, Songtao Yang, Yongkun Zhao, Yongkun Zhao, Xianzhu Xia, Xianzhu Xia, Xianzhu Xia   +26 more
doaj   +1 more source

Correlation Between Rift Valley Fever Virus (RVFV) Neutralizing Antibody Titers in Vaccinated Sheep and Effective Dose 50 (ED50) in Vaccinated Mice

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY, 2020
Rift valley fever is an arthropod-born, multispecies zoonotic viral disease. Control of RVF disease depends mainly on vector control and vaccination of susceptible animals. The present work aims to detect the correlation between Rift Valley Fever Virus (RVFV) neutralizing antibody titers in vaccinated sheep using Serum Neutralization test as in vitro ...
Nermeen G Shafik, Barghooth WM, Amal AM, Heba MG Abdel Aziz, Heba A. Khafagy   +4 more
openaire   +1 more source

High Seroprevalence of Rift Valley Fever and Evidence for Endemic Circulation in Mbeya Region, Tanzania, in a Cross-Sectional Study [PDF]

, 2012
Background: The Rift Valley fever virus (RVFV) is an arthropod-borne phlebovirus. RVFV mostly causes outbreaks among domestic ruminants with a major economic impact. Human infections are associated with these events, with a fatality rate of 0.5-2%. Since
Harun Machibya (175603), Ntinginya Elias, Elmar Saathoff, Petra Clowes, Leonard Maboko, Leonard Maboko (175605), Dobler, Gerhard, Nina Weller (175596), Clowes, Petra, Hoelscher, Michael, Elmar Saathoff (4991), Norbert Heinrich (175590), Weller, Nina, Michael Hoelscher, Gerhard Dobler, Gerhard Dobler (175607), Norbert Heinrich, Heinrich Norbert, Hoelscher Michael, Michael Hoelscher (151418), Dobler Gerhard, Petra Clowes (175598), Thomas Löscher, Harun Machibya, Kroidl, Inge, Machibya Harun, Loescher, Thomas, Saathoff, Elmar, Machibya, Harun, Inge Kroidl, Weller Nina, Kroidl Inge, Elias Ntinginya (175601), Nina Weller, Thomas Löscher (139093), Heinrich, Norbert, Maboko Leonard, Löscher Thomas, Saathoff Elmar, Inge Kroidl (151415), Maboko, Leonard, Elias Ntinginya, Ntinginya, Elias, Clowes Petra   +43 more
core   +2 more sources

In vitro and in vivo efficacy of a Rift Valley fever virus vaccine based on pseudovirus

Human Vaccines & Immunotherapeutics, 2019
Rift Valley fever virus (RVFV), a recognized category A priority pathogen, causes large outbreaks of Rift Valley fever with some fatalities in humans in humans and huge economic losses in livestock.
Jian Ma, Ruifeng Chen, Weijin Huang, Jianhui Nie, Qiang Liu, Youchun Wang, Xiaoming Yang   +6 more
doaj   +1 more source