Arm race between Rift Valley fever virus and host
Frontiers in Immunology, 2022 Rift Valley fever (RVF) is a zoonotic disease caused by Rift Valley fever virus (RVFV), an emerging arbovirus within the Phenuiviridae family of Bunyavirales that has potential to cause severe diseases in both humans and livestock.
Xiao Wang +8 more
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Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]
, 2010 Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Kosmider, R. +7 more
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Emerging Infectious Diseases, 2021 We detected Rift Valley fever virus (RVFV) IgM and IgG in human serum samples collected during 2018–2019 in northern KwaZulu-Natal Province, South Africa.
Janusz T. Pawęska +5 more
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Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice. [PDF]
PLoS ONE, 2018 Rift Valley fever (RVF) in humans is usually mild, but, in a subset of cases, can progress to severe hepatic and neurological disease. Rodent models of RVF generally develop acute severe clinical disease.
Jessica R Spengler +7 more
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The Rift Valley Fever Virus Replicative Cycle. [PDF]
, 2010 The Rift Valley fever virus (RVFV) is responsible for numerous, explosive epizootics throughout Africa and the Arabian Peninsula. The virus causes disease predominantly in humans and livestock, with sheep and cattle being particularly susceptible.
Piper, Mary Elise
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mSphere, 2021 Rift Valley fever virus (RVFV) is a mosquito-borne virus found throughout Africa and into the Middle East. It has a substantial disease burden; in areas of endemicity, up to 60% of adults are seropositive.
Haley N. Cartwright +2 more
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A hyper-attenuated variant of Rift Valley fever virus (RVFV) generated by a mutagenic drug (favipiravir) unveils potential virulence markers [PDF]
Frontiers in Microbiology, 2020 SUMMARY/ABSTRACT In a previous work, we showed that favipiravir, a promising drug with antiviral activity against a number of RNA viruses, led to the extinction of RVFV from infected cell cultures. Nevertheless, certain drug concentrations allowed the recovery of a virus variant showing increased resistance to ...
Belén Borrego, Alejandro Brun
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The consequences of reconfiguring the ambisense S genome segment of Rift Valley fever virus on viral replication in mammalian and mosquito cells and for genome packaging [PDF]
, 2013 Rift Valley fever virus (RVFV, family Bunyaviridae) is a mosquito-borne pathogen of both livestock and humans, found primarily in Sub-Saharan Africa and the Arabian Peninsula.
Benjamin Brennan (522804) +13 more
core +1 more source
Cell Reports, 2018 Summary: The Gn subcomponent of the Gn-Gc assembly that envelopes the human and animal pathogen, Rift Valley fever virus (RVFV), is a primary target of the neutralizing antibody response.
Elizabeth R. Allen +18 more
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An equine herpesvirus type 1 (EHV-1) vector expressing Rift Valley fever virus (RVFV) Gn and Gc induces neutralizing antibodies in sheep [PDF]
Virology Journal, 2017 Rift Valley fever virus (RVFV) is an arthropod-borne bunyavirus that can cause serious and fatal disease in humans and animals. RVFV is a negative-sense RNA virus of the Phlebovirus genus in the Bunyaviridae family. The main envelope RVFV glycoproteins, Gn and Gc, are encoded on the M segment of RVFV and known inducers of protective immunity.
Abdelrahman Said +4 more
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