Results 51 to 60 of about 3,020,850 (211)
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Advanced Science, EarlyView.Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
A rare case of right aortic arch with mirror-image branching and vascular ring in an adult patient
Radiology Case ReportsA right-sided aortic arch with mirror-image branching is a rare vascular anomaly, often associated with congenital heart defects. However, its occurrence with a vascular ring in the absence of cardiac abnormalities is extremely rare.
Salma El Aouadi +5 more
doaj +1 more source
Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications
Advanced Science, EarlyView.Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu +7 more
wiley +1 more source
An adult case of Kommerell’s diverticulum with a right-sided aortic arch
, 2017 The patient was a 56-year-old woman with Kommerell’s diverticulum associated with a right-sided aortic arch with mirror-image branching. No other congenital heart anomalies or vascular rings were observed.
Natsumi Iijima +4 more
core +1 more source
Advanced Science, EarlyView.Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana +19 more
wiley +1 more source
Surgical treatment strategies for patients with type A aortic dissection involving arch anomalies
Frontiers in Cardiovascular Medicine, 2022 ObjectiveThe aim of the study was to investigate surgical modalities and outcomes in patients with type A aortic dissection involving arch anomalies.MethodPatients with type A aortic dissection who underwent surgical treatment at our center between ...
Jiade Zhu +14 more
doaj +1 more source
Radiology Case Reports, 2019 Right aortic arch with mirror image branching (RAMI) is a rare congenital defect of the aorta. The exact incidence of RAMI in the general population is unclear. In RAMI the first branch arising from the arch is the left innominate artery, followed by the
D. Morosetti +7 more
semanticscholar +1 more source
Case Reports in Radiology, 2016 Anomalies of aortic arch are a common occurrence. Such anomalies of right sided aortic arch with its various branching patterns are of clinical importance.
Anagha R. Joshi +4 more
doaj +1 more source
Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source
, 2013 Comparison of patient characteristics of infants with right-sided (RAAA) and double-sided aortic arch anomaly (DAAA) (presented as median (range) or n (%)).
Gerd Schmalisch (320665) +6 more
core +1 more source